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  • 1965-1969  (188)
  • 1880-1889  (2)
  • 1860-1869
  • Cell & Developmental Biology  (190)
  • 1
    Electronic Resource
    Electronic Resource
    H3-proline incorporation into cartilage: Electron microscope autoradiographic observations (1968)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 124 (1968), S. 387-421 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Electron microscope autoradiography was used to study cartilage from regenerating limbs of adult newts, Triturus, after intraperitoneal injections of proline-3H. The labeling in the endoplasmic reticulum, small vesicles, Golgi vacuoles, ground cytoplasm and extracellular matrix was compared during the secretion of radioactive products. The data appear to indicate that a large part of the radioactive secretion probably leaves the cell after having been in only one cellular compartment. Although this compartment may be the endoplasmic reticulum, a considerable amount of radioactivity fluxes through the ground cytoplasm and the possibility cannot be excluded that some secretory components leave the cell directly from the ground cytoplasm. The data appear incompatible with the hypothesis that all the radioactivity seen in the extracellular matrix arrived there via a single pathway involving first the endoplasmic reticulum and then the Golgi vacuoles. It is not, however, incompatible with a hypothesis that a fraction of the radioactive product uses this pathway.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051240402
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  • 2
    Electronic Resource
    Electronic Resource
    Gross structure of the ear, nasal cavity and Paranasal sinuses of the chimpanzeeThis work was supported by the United States Air Force contract AF 29(600)-3021. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 155 (1966), S. 77-88 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Gross examination of the chimpanzee skull revealed that: there are three ethmoidal sinuses; the sphenoid sinus is immense and is divided into a superior and inferior part; the huge maxillary sinus contains a distinct bony canal for the nasolacrimal duct; the anterior and middle ethmoidal sinuses drain into the superior meatus; the frontal sinus drains via the middle ethmoid; the posterior ethmoid and sphenoid sinuses open into the sphenoethmoidal recess and also communicate with each other; the maxillary sinus opens into the middle meatus through a large ostium; the nasolacrimal duct drains into the inferior meatus; the mastoid process is small but contains a central cavity which communicates with the middle ear; the broad and smooth planum tympanum serves as the floor of the external auditory canal, the latter forming an angle of 30° with the horizontal; the tympanic membrane makes an angle of 30° with the floor of the canal and is deeply recessed antero-inferiorly; except for the extreme slope of the tympanic membrane and the malleus, the middle ear is similar to man; the inner ear is likewise similar; the carotid artery and the large carotid plexus lie in a definite osseous tube surrounded by pneumatized bone but attached to the periotic capsule; the chimpanzee is subject to otitis media.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091550109
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  • 3
    Electronic Resource
    Electronic Resource
    Direct adrenergic innervation of a teleost melanophoreSupported by USPHS Research grants 1 RO1 NB-06707-02, 5 RO1 NB-06092-03, by a research career program award (D. J.), 5-K3-NB-13,935-02, from the NIH and by a Research Professorship (to A.L.) from Research to Prevent Blindness, Inc. (1968)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 162 (1968), S. 501-504 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The possibility of sympathetic innervation to melanophores in fish was investigated using a catecholamine histochemical fluorescence method. Catecholamine-containing fibers were observed to be in close anatomic proximity to the conjunctival and dermal melanophores of the cunner (Tautogolabrus adspersus). It is suggested that the catecholamines released from these adrenergic fibers are capable of causing aggregation of pigment with blanching of skin color.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091620411
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  • 4
    Electronic Resource
    Electronic Resource
    Response of murine cutaneous nerves to skin painting with methylcholanthreneSupported by grants from the Medical Research Council of Ireland and from the Jane Coffin Childs Memorial Fund for Medical Research. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 154 (1966), S. 617-633 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A saturated solution of 20-methylcholanthrene in benzene was applied to the ear and trunk of 59 BALB mice. The effects upon cutaneous innervation were compared with that of 50% turpentine in acetone (13 mice) and of skin abrasion with sandpaper (11 mice). Silver impregnation techniques showed that the carcinogentreated epidermis was invaded by nerve fibers whose number was related to the degree of epidermal hyperplasia, but not to the period of treatment or to the animals' age at the time of first painting. Hair follicles showed changes in the size, number and length of nerve endings. Growth of cutaneous nerves was already evident on the fourth day of exposure to methylcholanthrene. Turpentine elicited only a slight neural reaction after 60 days; and the sandpaper treatment was without effect.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091540309
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  • 5
    Electronic Resource
    Electronic Resource
    Pseudoepiphyses or notches in the non-epiphyseal end of metacarpal bones in healthy childrenThis work was supported in part by AM-03816 from the National Institutes of Health, Bethesda, Maryland. (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 159 (1967), S. 263-272 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Longitudinal series of hand x-rays from healthy white children (116 boys, 118 girls) of Fels growth studies were investigated. Notchings of the nonepiphyseal end of the first, second and fifth metacarpal bones were found in every child. Beginning from infancy or early childhood, the notchings follow a sequence of developmental stages (obtuse-angle; acute-angle; cleft: underlying, edge-to-edge, overjutting; and fusion) until they disappear one to one and one-half years before onset of puberty. The notching intensity in the second and the fifth metacarpal bones was rated. A moderate degree of association in notching intensity was demonstrated between brothers and sisters.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091590304
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  • 6
    Electronic Resource
    Electronic Resource
    The origin and survival of gastric parietal cells in the mouse (1968)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 162 (1968), S. 99-109 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Using microradioautography, the origin of the gastric parietal (and zymogen) cells was deduced by observing the time of appearance of labelled parietal cells in relation to the other labelled cells in the gastric mucosa. In order to see whether the parietal cell divides in the adult mouse, time grain count curves of the labelled parietal cells were made from animals which were killed at 1-291 days after thymidine 3H injection DPT). Parietal cell survival was followed by observing the disappearance of the labelled parietal cell population. Parietal cells appear to be entirely derived from other cells since a significant number of labelled parietal cells does not appear unless the animal is allowed to survive for several days. Parietal cells do not appear unless the animal is allowed to survive for several days. Parietal cells do not seem to undergo mitosis in the adult mouse because the time grain count curves did not shift with time. Although a few labelled parietal cells persisted in the 291 DPT animals, a large majority of the labelled parietal cells disappeared by 90 DPT and had a half life of roughly 23 days. This suggests an element of renewal for the parietal cell population.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091620109
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  • 7
    Electronic Resource
    Electronic Resource
    Temporal and cytological aspects of fertilization and early development in the guinea pig, Cavia porcellus (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 165 (1969), S. 411-429 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A study was made of 174 eggs recovered from 58 guinea pigs killed between the first and sixth days after mating, and the cytological details from the stage of sperm penetration to the pre-implantation blastocyst described. Eighty-nine percent of the expected number of eggs were recovered, and 97% of these were fertilized. Embryonic development proceeded from pronuclear and 2-cell eggs on day 1 to pre-implantation blastocysts on day 6, the duration of each of the early cleavage stages being of approximately 24 hours. No progressive loss of embryos was found over this period, all the eggs recovered on days 4, 5 and 6 being regarded as developing normally. Passage of embryos from the Fallopian tubes to the uterus commenced on the afternoon of day 3, and the majority of embryos entered the uterus shortly after this time at the stage of 8- to 16-cells. The tail of the fertilizing spermatozoon was detected in the cytoplasm of all eggs examined on day 1, in most of those examined on day 2, and frequently persisted up to the 8-cell stage. Three dispermic eggs, each containing two distinct cytoplasmic sperm tails, were found: one of these was at the pronuclear stage, the other two being considered of 4- and 6-cells respectively. Properties of adhesiveness were shown by blastocysts recovered shortly before implantation on day 6, but the characteristic “zona processes” were not seen.
    Additional Material: 7 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091650310
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  • 8
    Electronic Resource
    Electronic Resource
    Fertilization and early development after radiocobalt irradiation of rabbit oocytes and sperm in the female tract (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 154 (1966), S. 713-725 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: One hundred and seven female rabbits were divided into three groups and irradiated with 400 r from a radiocobalt source. The first group (71 animals) was irradiated before or 4-12 hours after mating and an ovulating injection of H.C.G. The second group (27 animals) were irradiated at about the same time after injection but inseminated after irradiation. The third group (9 animals) were inseminated with spermatozoa which had been irradiated in other females.The ova were recovered at various times for the determination of fertilization, cleavage, and blastocyst formation. Groups of animals were autopsied 14 or 29 days later for the determination of fetal development. The fertilization rate was not disturbed whether sperm, oocytes, or both were irradiated. The disturbance of nuclear material, the aberration of chromosomes, the retardation of cleavage, the fragmentation of cytoplasm, and the failure of blastocyst formation and embryonic development were observed especially whenever oocytes were irradiated. Irradiation of oocytes before mating and injection appeared to be less harmful but no differential effects were observed when irradiation was at 4, 6, 8, 10 or 12 hours after ovulating injection or when oocytes alone or both the oocytes and sperm were irradiated, probably due to the dosage being too high. Irradiation of sperm in the female tract was less harmful, normal blastocysts and apparently normal fetuses were obtained when nonirradiated ova were fertilized by such spermatozoa.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091540403
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  • 9
    Electronic Resource
    Electronic Resource
    The myelinated fibers in the aortic nerve of the swine (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 159 (1967), S. 41-45 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The aortic nerves of 24 Chester White swine were identified electrophysiologically by the synchronization of the recorded action potentials with the cardiac cycle; and the occurrence of the maximum firing rates observed on the oscilloscope during systole. The aortic nerve, thus identified, was traced to the aortic arch in two preparations. The left aortic nerve was a separate bundle in 15 of 24 (62.5%) swine investigated. In the remaining 37.5% of the swine the nerve was dissected from within the vagus after identification at the level of the nodose ganglion. At this level the aortic nerve leaves the ganglion with the superior laryngeal nerve, runs caudomedially with it a short distance, then loops back laterally into the vagus to run caudally to the arch of the aorta. An aortic nerve was not observed in the right vagus nor in the sympathetic trunk of either side. The myelinated fibers counted from six aortic nerves were less than 10 μ in diameter with the majority in the 2-6 μ range, and averaged 542 in number.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091590107
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  • 10
    Electronic Resource
    Electronic Resource
    The terpene-producing glands of a phasmid insect cell morphology and histochemistry (1966)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 119 (1966), S. 143-159 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The defensive glands of Anisomorpha buprestoides produce the terpene toxicant anisomorphal. Each gland consists of a cuticular secretion reservoir surrounded by the secretory epithelium and the musculature which serves to compress the gland and expel the secretion. Two types of cells make up the secretory epithelium: a squamous layer next to the cuticular reservoir and a layer of larger secretory cells responsible for production of the toxicant. The microvilli-laden plasma membrane of each secretory cell is invaginated to form a central cavity. It appears that secretory products pass into the central cavity and then flow out to the gland reservoir via an efferent cuticular ductule contained within the squamous epithelial cell.Histochemical techniques demonstrate lipid reserves, carboxylic esterases, a variety of phosphatases, and an alcohol dehydrogenase, within the secretory cells. It is suggested that the lipid reserves are precursors of the terpenoid toxicant, that a mevalonic kinase has been histochemically demonstrated by the phosphatase test, and that an unusual alcohol dehydrogenase is active in the final steps of toxicant synthesis. The histochemical evidence is consistent with the hypothesis that anisomorphal is produced via the mevalonic acid pathway.
    Additional Material: 28 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051190204
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