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  • 1
    Electronic Resource
    Electronic Resource
    Hamster costovertebral organ lipogenesis in vitro and in vivo: effects of cerulenin (1986)
    Springer
    Archives of dermatological research 278 (1986), S. 486-490 
    Details
    ISSN: 1432-069X
    Keywords: Costovertebral gland ; Lipogenesis ; Cerulenin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An assay for lipid synthesis by hamster costovertebral organ (CVO) in vivo is described. When sodium [1-14C]acetate is injected intraperitoneally into male hamsters, maximum labeling of CVO lipids occurs after 5 min and remains constant for more than 40 min following injection. The major products of in vivo labeling are polar lipids, triglycerides, and sterols. The distribution of radiolabeled lipid products in vivo is similar to that obtained from incubation of CVO punch biopsy specimens with [1-14C]acetate in vitro. Castration results in an〉80% inhibition of CVO lipid synthesis as measured using in vitro or in vivo techniques. Cerulenin inhibited de novo fatty acid synthesis by the 100,000xg supernatant of a CVO homogenate and the incorporation of [1-14C]acetate into fatty acids by CVO biopsies in vitro. Topical application of cerulenin to the CVO did not inhibit synthesis of radiolabelled lipids from [1-14C] acetate in vivo. The in vivo assay provides a necessary means of determining the physiological significance of in vitro results obtained when assaying for inhibitors of sebaceous gland lipogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00455169
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  • 2
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    New Poems by Sir Edward Dyer (1935)
    Oxford : Periodicals Archive Online (PAO)
    Review of English studies. 11 (1935) 466 
    Details
    ISSN: 0034-6551
    Topics: English, American Studies
    Notes: NOTES AND OBSERVATIONS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:0091-1935-011-00-000025
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  • 3
    Electronic Resource
    Electronic Resource
    Gross structure of the ear, nasal cavity and Paranasal sinuses of the chimpanzeeThis work was supported by the United States Air Force contract AF 29(600)-3021. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 155 (1966), S. 77-88 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Gross examination of the chimpanzee skull revealed that: there are three ethmoidal sinuses; the sphenoid sinus is immense and is divided into a superior and inferior part; the huge maxillary sinus contains a distinct bony canal for the nasolacrimal duct; the anterior and middle ethmoidal sinuses drain into the superior meatus; the frontal sinus drains via the middle ethmoid; the posterior ethmoid and sphenoid sinuses open into the sphenoethmoidal recess and also communicate with each other; the maxillary sinus opens into the middle meatus through a large ostium; the nasolacrimal duct drains into the inferior meatus; the mastoid process is small but contains a central cavity which communicates with the middle ear; the broad and smooth planum tympanum serves as the floor of the external auditory canal, the latter forming an angle of 30° with the horizontal; the tympanic membrane makes an angle of 30° with the floor of the canal and is deeply recessed antero-inferiorly; except for the extreme slope of the tympanic membrane and the malleus, the middle ear is similar to man; the inner ear is likewise similar; the carotid artery and the large carotid plexus lie in a definite osseous tube surrounded by pneumatized bone but attached to the periotic capsule; the chimpanzee is subject to otitis media.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091550109
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