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  • 1
    Electronic Resource
    Electronic Resource
    Effect of antibody to the hemin-controlled translational repressor in rabbit reticulocyte lysate
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression 908 (1987), S. 123-130 
    Details
    ISSN: 0167-4781
    Keywords: (Rabbit reticulocyte) ; Anti-HCR antibody ; Hemin ; Hemin-controlled translational repressor ; Translational repressor
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4781(87)90051-0
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  • 2
    Electronic Resource
    Electronic Resource
    Differential effect of Mn^2^+ on the hemin-controlled translational repressor and the double-stranded RNA-activated inhibitor
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression 740 (1983), S. 255-263 
    Details
    ISSN: 0167-4781
    Keywords: (Rabbit reticulocyte) ; Hemin ; Mn^2^+ ; Protein kinase ; Protein synthesis ; Translation
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4781(83)90134-3
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  • 3
    Electronic Resource
    Electronic Resource
    Characterization of a rabbit reticulocyte supernatant factor that reverses the translational inhibition of hemin deficiency
    Amsterdam : Elsevier
    BBA Section Nucleic Acids And Protein Synthesis 654 (1981), S. 219-226 
    Details
    ISSN: 0005-2787
    Keywords: (Rabbit reticulocyte) ; Hemin ; Polypeptide chain initiation ; Protein synthesis ; Translational repressor
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2787(81)90175-1
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  • 4
    Electronic Resource
    Electronic Resource
    Equilibration of methionine into the Met-tRNA pool of rabbit reticulocyte lysates - Additional evidence that deacylation of ribosomal subunit-bound Met-tRNA"f does occur in heme-deficiency
    Amsterdam : Elsevier
    FEBS Letters 160 (1983), S. 249-254 
    Details
    ISSN: 0014-5793
    Keywords: Deacylation ; Hemin ; Met-tRNA ; Protein synthesis ; Reticulocyte lysate ; Translational control
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)80976-4
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  • 5
    Electronic Resource
    Electronic Resource
    Ribose administration during exercise: Effects on substrates and products of energy metabolism in healthy subjects and a patient with myoadenylate deaminase deficiency (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 151-155 
    Details
    ISSN: 1432-1440
    Keywords: Myoadenylate deaminase ; AMP-deaminase ; Deficiency ; Ribose ; Lactate ; Ammonia ; Hypoxanthine ; Muscle ; Metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nine healthy men and a patient with myoadenylate deaminase deficiency were exercised on a bicycle ergometer (30 minutes, 125 Watts) with and without oral ribose administration at a dose of 2 g every 5 minutes of exercise. Plasma or serum levels of glucose, free fatty acids, lactate, ammonia and hypoxanthine and the urinary hypoxanthine excretion were determined. After 30 minutes of exercise without ribose intake the healthy subjects showed significant increases in plasma lactate (p〈0.05), ammonia (p〈0.01) and hypoxanthine (p〈0.05) concentrations and a decrease in serum glucose concentration (p〈0.05). When ribose was administered, the plasma lactate concentration increased significantly higher (p〈 0.05) and the increase in plasma hypoxanthine concentration was no longer significant. The patient showed the same pattern of changes in serum or plasma concentrations with exercise with the exception of hypoxanthine in plasma which increased higher when ribose was administered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01665856
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  • 6
    Electronic Resource
    Electronic Resource
    Serum levels of glucose, insulin, and C-peptide during long-term D-ribose administration in man (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 31-36 
    Details
    ISSN: 1432-1440
    Keywords: (D-)ribose ; Glucose ; Insulin ; C-peptide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary D-ribose was given orally and/or intravenously to nine healthy subjects at doses ranging from 83.3 to 222.2 mg/kg per hour for at least four hours. The serum ribose level increased in a dose-dependent manner to maximum concentrations of 75 to 85 mg/dl. The serum glucose level decreased after the beginning of continuous ribose administration and was reduced as long as ribose was being administered. The oral or intravenous administration of 166.7 mg/kg per hour of ribose resulted in a 25% decrease in serum glucose. Higher intravenous doses of ribose did not provoke a further decrease in serum glucose concentration. Oral administration of 166.7 mg/kg per hour led to an increase in serum insulin concentrations from a mean of 8.4 (range 6.4–11.5) to 10.4 (range 6.3–15.4) μU/ml (p〈0.05). In contrast, intravenous administration did not change serum insulin concentrations significantly. The serum c-peptide concentration remained unchanged regardless of treatment. We conclude that the variations in plasma insulin concentrations do not account for the observed decrease in mean serum glucose concentrations accompanying D-ribose administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01649054
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  • 7
    Electronic Resource
    Electronic Resource
    Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency (1989)
    Springer
    Journal of molecular medicine 67 (1989), S. 1205-1213 
    Details
    ISSN: 1432-1440
    Keywords: (D-)ribose ; Metabolism ; Myoadenylate ; (adenylate-, AMP-)deaminase deficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary D-ribose was administered orally or intravenously over at least 5 h to eight healthy volunteers and five patients with myoadenylate deaminase deficiency. Intravenous administration rates were 83, 167, and 222 mg/kg/h, which were well tolerated but oral administration of more than 200 mg/kg/h caused diarrhea. The average steady state serum ribose level ranged between 4.8 mg/100 ml (83 mg/kg/h, oral administration) and 81.7 mg/100 ml (222 mg/kg/h, intravenous administration). Serum glucose level decreased during ribose administration. The intestinal absorption rate of orally administered ribose was 87.8%–99.8% of the intake at doses up to 200 mg/kg/h without first pass effect. Urinary losses were 23% of the intravenously administered dose at 222 mg/kg/h. Ribose appeared to be excreted by glomerular filtration without active reabsorption; a renal threshold could not be demonstrated. The amount of ribose transported back from the tubular lumen depended on the serum ribose level. There was no difference in ribose turnover in healthy subjects and patients with MAD deficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01716208
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  • 8
    Electronic Resource
    Electronic Resource
    Ergometer exercise in myoadenylate deaminase deficient patients (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 461-465 
    Details
    ISSN: 1432-1440
    Keywords: AMP deaminase ; Myoadenylate deaminase deficiency ; Muscular exercise ; Hypoxanthine ; Ammonia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three patients with primary myoadenylate deaminase deficiency were subjected to exercise on a bicycle ergometer at 125 W for 30 minutes. Blood samples prior to, during, and at the end of exercise were analyzed for lactate, ammonia, and hypoxanthine. In addition, urinary hypoxanthine excretion was measured. In these patients the serum lactate level increased to concentrations between 7.9 and 9.0 mmol/1 at the end of exercise whereas the mean lactate level in nine control subjects at the end of exercise was 3.3 mmol/l (range 1.1–8.1 mmol/l). There was no difference to control subjects in the exercise-induced increase in plasma levels of ammonia and hypoxanthine or in the increase in urinary hypoxanthine excretion. The findings support the hypothesis of a reduced substrate supply to the citric acid cycle in myoadenylate deaminase deficiency. The normal formation of ammonia and hypoxanthine excludes a marked loss of adenine nucleotides in working muscles in these patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180060
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  • 9
    Electronic Resource
    Electronic Resource
    Continuously tunable, split-cavity gyrotrons (1985)
    Springer
    International journal of infrared and millimeter waves 6 (1985), S. 1237-1254 
    Details
    ISSN: 1572-9559
    Keywords: gyrotron ; millimeter-wave ; microwave ; electron cyclotron resonance maser ; resonant cavities ; frequency tuning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The cavity of the University of Sydney gyrotron, GYROTRON IIIB, is split in two longitudinally to allow and frequency that lies between the fixed cavity resonances to be accessed by mechanically changing the separation of the two halves. The rate of change in resonant frequency with separation is greatest if the minor axis of the cavity cross-section is the one undergoing change. Results obtained with the latest cavity demonstrate this and show excellent agreement with theory.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01013212
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  • 10
    Electronic Resource
    Electronic Resource
    Tuneable millimeter-wave gyrotrons (1982)
    Springer
    International journal of infrared and millimeter waves 3 (1982), S. 725-734 
    Details
    ISSN: 1572-9559
    Keywords: gyrotron ; millimeter-wave ; microwave cavities ; microwaves ; electron cyclotron maser
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In the course of developing a low-power, tuneable millimeter-wave source, two gyrotrons have been constructed. Gyrotron I was a fixed-frequency device operating at 120 GHz while Gyrotron II produced more than 20 lines in the frequency range 130 to 260 GHz. The design of tuneable gyrotrons is discussed with reference to the Gyrotron II results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01009730
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