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  • Life and Medical Sciences  (5)
  • Amino acid sequence  (3)
  • (Human erythrocyte)  (2)
  • Anorectal malformation  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Structure and functional properties of lipoprotein lipase
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism 1123 (1992), S. 1-17 
    Details
    ISSN: 0005-2760
    Keywords: Amino acid sequence ; Hyperlipoproteinemia ; Kinetics ; Lipoprotein lipase ; Mutation ; cDNA sequence
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2760(92)90165-R
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Bile salt-activated lipase. A multiple function lipolytic enzyme
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism 1166 (1993), S. 1-19 
    Details
    ISSN: 0005-2760
    Keywords: Amino acid sequence ; Bile salt ; Carboxylesterase ; Enzyme kinetics ; Lipase ; Substrate specificity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2760(93)90277-G
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  • 3
    Electronic Resource
    Electronic Resource
    Human erythrocyte NADH: (acceptor) oxidoreductase. Kinetic properties and competitive substrate inhibition by ferricyanide
    Amsterdam : Elsevier
    BBA - Enzymology 616 (1980), S. 22-29 
    Details
    ISSN: 0005-2744
    Keywords: (Human erythrocyte) ; Competitive substrate inhibition ; Ferricyanide ; Kinetic mechanism ; NADH dehydrogenase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2744(80)90259-4
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Kinetic evidence for the allosteric substrate inhibition of human erythrocyte acetylcholinesterase
    Amsterdam : Elsevier
    BBA - Enzymology 612 (1980), S. 67-72 
    Details
    ISSN: 0005-2744
    Keywords: (Human erythrocyte) ; Acetylcholinesterase ; Allosteric inhibition
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2744(80)90279-X
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Heterogeneity in cDNA clones encoding rice glutelin
    Amsterdam : Elsevier
    FEBS Letters 222 (1987), S. 135-138 
    Details
    ISSN: 0014-5793
    Keywords: (Rice) ; Amino acid sequence ; Glutelin ; Nucleotide sequence ; cDNA clone
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(87)80206-5
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  • 6
    Electronic Resource
    Electronic Resource
    The use of augmented-pressure colostography in imperforate anus (1997)
    Springer
    Pediatric surgery international 12 (1997), S. 383-385 
    Details
    ISSN: 1437-9813
    Keywords: Key words Colostogram ; Imperforate anus ; Anorectal malformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Colostomy is recommended in most newborns with imperforate anus (IA), except those with low-type anorectal malformations (ARM). Accurate demonstration of the anatomy of any associated fistula between the rectum and the urogenital tract is essential for optimal surgical management. Augmented-pressure distal colostography is recommended to fulfill this requirement prior to definitive surgical repair of IA. We examined 12 cases of high or intermediate-type ARM using this technique, which clearly demonstrated the distal perineal anatomy. All were confirmed at posterior sagittal anorectoplasty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003830050157
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  • 7
    Electronic Resource
    Electronic Resource
    The use of augmented-pressure colostography in imperforate anus (1997)
    Springer
    Pediatric surgery international 12 (1997), S. 383-385 
    Details
    ISSN: 1437-9813
    Keywords: Colostogram ; Imperforate anus ; Anorectal malformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Colostomy is recommended in most newborns with imperforate anus (IA), except those with low-type anorectal malformations (ARM). Accurate demonstration of the anatomy of any associated fistula between the rectum and the urogenital tract is essential for optimal surgical management. Augmented-pressure distal colostography is recommended to fulfill this requirement prior to definitive surgical repair of IA. We examined 12 cases of high or intermediate-type ARM using this technique, which clearly demonstrated the distal perineal anatomy. All were confirmed at posterior sagittal angorectoplasty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01076945
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells (1995)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 58 (1995), S. 393-402 
    Details
    ISSN: 0730-2312
    Keywords: adipocytes ; bone morphogenetic proteins ; differentiation ; bone marrow stromal cells ; transforming growth factor β ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The bone morphogenetic proteins were originally identified based on their ability to induce ectopic bone formation in vivo and have since been identified as members of the transforming growth factor-β gene superfamily. It has been well established that the bone morphogenetic cytokines enhance osteogenic activity in bone marrow stromal cells in vitro. Recent reports have described how bone morphogenetic proteins inhibited myogenic differentiation of bone marrow stromal cells in vitro. In vivo, bone marrow stromal cells differentiate along the related adipogenic pathway with advancing age. The current work reports the inhibitory effects of the bone morphorphogenetic proteins on adipogenesis in a multipotent murine bone marrow stromal cell line, BMS2. When exposed to bone morphogenetic protein-2, the pre-adipocyte BMS2 cells exhibited the expected induction of the osteogenic-related enzyme, alkaline phosphatase. Following induction of the BMS2 cells with adipogenic agonists, adipocyte differentiation was assessed by morphologic, enzymatic, and mRNA markers. Flow cytometric analysis combined with staining by the lipophilic fluorescent dye, Nile red, was used to quantitate the extent of lipid accumulation within the BMS2 cells. By this morphologic criteria, the bone morphogenetic proteins inhibited adipogenesis at concentrations of 50 to 500 ng/ml. This correlated with decreased levels of adipocyte specific enzymes and mRNAs. The BMS2 pre-adipocytes constitutively expressed mRNA encoding bone morphogenetic protein-4 and this was inhibited by adipogenic agonists. Together, these findings demonstrate that bone morphogenetic proteins act as adipogenic antagonists. This supports the hypothesis that adipogenesis and osteogenesis in the bone marrow microenvironment are reciprocally regulated.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240580312
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  • 9
    Electronic Resource
    Electronic Resource
    Unique 3′-untranslated sequence of insulin-like growth factor-I isolated from human placenta (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 29 (1991), S. 238-244 
    Details
    ISSN: 1040-452X
    Keywords: IGF-IA ; Long 3′-end ; Expression ; Transcripts sizes ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: A cDNA clone of 525 bp corresponding to the 3′-untranslated region of insulin-like growth factor-I was isolated from a human placenta library. The sequence of this clone extended 200 nucleotides downstream from the previously reported 3′-end of IGF-IA cDNA, indicating the existence of IGF-IA transcripts having an even larger 3′-untranslated region. By using this clone for RNA transfer blot hybridization, it was shown that this longer 3′-untranslated region is included in the 7.5- and 5.0-kb transcripts, but not in the 1.1- and 0.9-kb transcripts. It is also apparent that transcripts bearing the extended 3′-untranslated sequence are highly expressed in human placenta.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1080290305
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  • 10
    Electronic Resource
    Electronic Resource
    Pattern of glucose transporter (Glut 1) expression in embryonic brains is related to maturation of bood-brain barrier tightness (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 193 (1992), S. 152-163 
    Details
    ISSN: 0002-9106
    Keywords: Cerebral endothelium ; Development ; Immunocytochemistry ; Rat ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A constant supply of blood-borne glucose is vital to cerebral metabolism. Although transport of glucose into the nervous tissue, effectively separated from the blood by a functional barrier (the blood-brain barrier, BBB), is one of the essential properties of the cerebral endothelium, little is known about its metabolic regulation and developmental expression in the BBB. In this study we provide evidence by immunocytochemistry that the pattern of the brain endothelial glucose transporter in rat brains (BBB-GT), immunologically homologous with the human hepatoma (G2), human erythrocyte transporter (Glut 1), changes with BBB maturation. While the neuroepithelium at embryonic days 12 and 13 shows a high incidence of immuno-detectable BBB-GT, vascularisation of the cerebral anlage and subsequent development of vascular tightness, as evidenced by intravascularly applied horseradish peroxidase and fluorescinated dextrans, is accompanied by a significant reduction BBB-GT expression in neuroepithelial cells and confinement of BBB-GT expression to the cerebral endothelium. Immunoblots and Northern blots of embryonic brain homogenates corroborate this change in BBB-GT expression in the brain anlage at the time of BBB maturation. However, low molecular weight glucose transporters, presumed to be of non-endothelial origin, are less dramatically reduced. The development of BBB tightness, therefore, seems to play a pivotal role in the pattern of BBB-GT expression during brain differentiation.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001930207
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