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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 157 (1997), S. 39-44 
    ISSN: 1432-1076
    Keywords: Key words Solitary maxillary central incisor ; Holoprosencephaly ; Congenital nasal pyriform aperture Chromosome 18p- ; or ring(18) ; Stenosis ; Hypopituitarism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Solitary maxillary central incisor (SMCI) and congenital nasal pyriform aperture stenosis (CNPAS) have been reported as an isolated morphogenic defect or associated with pituitary deficiency, holoprosencephaly, ocular coloboma, or chromosomal abnormalities. We report two cases and analyse 40 cases of SMCI and 24 cases of CNPAS, including 15 cases of combined SMCI and CNPAS, obtained from the literature. Of the patients with SMCI, 69% had short stature, 48% growth hormone deficiency or hypopituitarism, 23% pituitary absence or hypoplasia, and 17% had del (18p-) or r(18). Of the patients with CNPAS, 63% had SMCI, 75% were short, 43% had hypopituitarism or growth hormone deficiency, 36% had pituitary or CNS anomaly, and 33% had del (18p), r(18), or del (13q). Conclusions Solitary maxillary central incisor and congenital nasal pyriform aperture stenosis can be a diagnostic clue to pituitary hypofunction, CNS, ophthalmological and cytogenic anomalies.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 5416-5416 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Rare-earth/transition-metal alloys can exhibit magnetostrictive strains of order 0.17% in modest fields. Larger strains are of interest for many actuator applications. Certain alloys that undergo martensitic transformations exhibit a shape–memory effect that can yield strains up to 20% upon heating the deformed martensitic phase and they can show superelasticity upon application of a small stress. These methods of activation can be a disadvantage for many applications; magnetic activation of a shape–memory effect is desired. Several magnetic shape–memory alloys exist, among them intermetallics based on Ni2MnGa, which are the subject of this work. These materials experience a 6.6% c-axis contraction on cooling through the martensitic transition temperature, which is near 273 K; this strain is accommodated by formation of an ensemble of strained twin crystals separated by twin boundaries. Strains of several percent could be produced magnetically if the twin boundaries could be moved under application of a magnetic field. We report observations of strains of nearly 0.2% induced along [001] in unstressed crystals of Ni2MnGa with magnetic fields of 8 kOe applied at 265 K (Fig. 1). (This strain is an order of magnitude larger than the magnetostrictive strain we measure in the parent Heusler phase at 283 K.) Our data suggest that these giant strains are associated with the superelastic motion of twin boundaries in the martensitic phase, which is stable below about 274 K; the strength of the measured anisotropy energy density, MSHa/2 is comparable to the elastic energy density, eσ/2, needed for superelastic twin boundary motion.1 The strains we observe are equivalent to those achieved in terfenol-D and represent only a small fraction of the strain available if the twin variants of the martensitic phase can be oriented prior to application of a field. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Single-crystal Ni2MnGa shows a nearly 0.2% strain under a magnetic field of 8 kOe at −8 °C. Polycrystalline samples have been prepared near stoichiometry to study the composition dependence of the magnetic and elastic properties. A narrow band of compositions has been found having a range of Curie and martensitic transformation temperatures, Tc and T0, extending to above room temperature. The compressive stress–strain characteristics in variable transverse field were studied in samples selected to have T0 just below room temperature. Stress-induced martensite was observed as expected and the magnetic field was applied under fixed load for various stresses. A transverse field of 3200 Oe caused the sample to strain under load doing work that increased up to 1.3 J/kg with increasing volume fraction of stress-induced martensite. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 69 (1996), S. 1966-1968 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Strains of nearly 0.2% have been induced along [001] in unstressed crystals of Ni2MnGa with magnetic fields of 8 kOe applied at 265 K. These stains are associated with the superelastic motion of twin boundaries in the martensitic phase that is stable below about 274 K. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Crystal Growth 135 (1994), S. 224-228 
    ISSN: 0022-0248
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    FEBS Letters 222 (1987), S. 135-138 
    ISSN: 0014-5793
    Keywords: (Rice) ; Amino acid sequence ; Glutelin ; Nucleotide sequence ; cDNA clone
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1920
    Keywords: CT ; Intracranial haemorrhage ; Hypoprothrombinaemia ; Thrombocytopenia ; Haemophilia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intracranial haemorrhage is a serious problem in haemostatic disorders in children. Intracranial bleeding is sometimes more marked than suspected clinically. Computed tomography (CT) permits accurate, sensitive diagnosis of intracranial haemorrhage. We report 13 patients; 3 patients with hypoprothrombinaemia, 4 patients with thrombocytopenia or platelet dysfunction and 6 with haemophilia A, B or Von-Willebrand's disease. One patient with hypoprothrombinaemia had a subarachnoid hemorrhage (SAH), one a subdural haematoma (SDH) and the third a combination of SAH, SDH and intracerebral haematoma (ICH). One patient with thrombocytopenia or platelet dysfunction had a SDH, while the others had ICH. In the six patients with haemophilia A, B or Von-Willebrand's disease, there were four examples of ICH, five of SAH and six of SDH. A neurosurgical procedure was performed in only one patient. Three children died of serious intracranial complications with uncal herniation.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1434-0879
    Keywords: Urolthiasis ; Obstructive uropathy ; Percutaneous nephrostomy ; Hypercalciuria ; Creatinine clearance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thirteen urolithiasis patients with unilateral obstructive uropathy were treated with percutaneous nephrostomy (PCN) either for urinary diversion, endopyelotomy, nephrolithtotmy or chemolysis. After percutaneous nephrostomy, the indvidual urine volume, creatinine clearance (Ccr), urinary absolute and fractional excretions of sodium, potassium, calcium, magnesium and inorganic phosphate were measured separately in timed urine collections from a pigtail catheter and from the urethra. The data showed that Ccr and the absolute urinary excretions of sodium, potassium, calcium, magnesium and inorganic phosphate were significantly lower in the PCN kidney immediately or 2 days after relief of obstruction. The ratio of total urinary calcium excretion to urinary creatinine excretion in the obstructed kidney was significantly greater than that in the contralateral kidney. The fractional excretions of calcium and magnesium increased as renal function decreased. The results showed that when the total Ccr is below normal, the apparent excretion of urinary calcium will be underestimated. However, when the total Ccr of patients is within normal range, hypercalciuria may be detected adequately and thus favors early implementation of an appropriate therapeutic strategy.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1434-0879
    Keywords: MDCK cells ; Allopurinol ; Shock waves ; Lithotripsy ; Calcium signalling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Allopurinol has been reported to ameliorate the side effects in patients following shock wave lithotripsy (SWL); however, the mechanism has not been studied. We have examined the protective effect of allopurinol on Madin-Darby canine kidney (MDCK) cells after shock wave exposure (SWE) by determining the release of aspartate aminotransferase (ASAT) and lactate dehydrogenase (LD), and the resting cytosolic Ca2+ concentration ([Ca2+]i). In SWE-treated cells, the release of ASAT and LD increased immediately, but largely transiently, by approximately 23% and 5-fold over control, respectively. Within 1–6 h after SWE there was a gradual rise in the resting [Ca2+]i of 16–137% above control. Allopurinol did not affect the transient enzyme release but blocked the long-term rises in the resting [Ca2+]i. The transient changes in [Ca2+]i evoked by two hormones, ATP and bradykinin, and a drug that releases Ca2+ from internal Ca2+ stores, thapsigargin, were only slightly affected in allopurinol-treated cells. We conclude that the protection conferred by allopurinol on patients treated with SWL might involve a direct protection of the kidney cells by maintaining a normal resting [Ca2+]i.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-6776
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary A new microbial isolate, Bacillus sp. U88, transformed 12-hydroxyoctadecanoic acid to 12,15-, 12,16- and 12,17-dihydroxyoctadecanoic acids when grown aerobically in 1 % yeast extract medium at 30°C and shaken at 250 rpm for 5 days. These three dihydroxyfatty acids were derivatized with Trimethylsilyl ether and identified by GC-MS analysis. The yield of 12,15-, 12,16- and 12,17-dihydroxyoctadecanoic acids after 5 day incubation were 2.8 %, 7.1 % and 1.1 %, respectively.
    Type of Medium: Electronic Resource
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