ISSN:
1434-9949
Keywords:
Hip
;
HLA-DRB1*0405
;
Joint destruction
;
Knee
;
Rheumatoid arthritis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract To determine the prognostic factors for knee and/or hip joint destruction in rheumatoid arthritis (RA) patients, we typed 379 RA patients for HLA-DRB1 alleles and analysed the antigen frequencies. The DRB1*0405 antigen frequency in RA patients who underwent total knee replacement and/or total hip replacement was significantly higher than in those who did not have replacements, which meant that DRB1*0405 was associated with knee and/or hip joint destruction. This finding may be of value for predicting knee and/or hip joint destruction in RA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01451284
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