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  • 10-Jahres-Ergebnisse  (1)
  • Acid inhibitory drugs  (1)
  • Cerebellum  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 337 (1972), S. 119-134 
    ISSN: 1432-2013
    Keywords: Deiters Neurones ; Excitation ; Inhibition ; Cerebellum ; Ascending Pathways
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out on cats anesthetized with chloralose, small doses of Thiopental being added in about half of the animals. Recordings were made from neurones located in Deiters' nucleus. Single shocks applied to the spinal cord evoked membrane potential changes consisting of different types of PSPs. Current analysis revealed: EPSPs, IPSPs, and potential changes due to disinhibition; such components differing in their latencies. Upon stimulation at C2, there were EPSPs with brief (mean 1.7 ms) and longer (mean 5.8 ms) latencies, denoted “EE” and “CE”, respectively. Also, IPSPs showed up with brief (mean 3.6 ms, “MI”) and longer (mean 7.3 ms, “CI”) latencies. Moreover, there was a prolonged inhibition usually turning into a longlasting (up to several hundred milliseconds) disinhibitory depolarization. Of Deiters neurones exhibiting PSPs upon spinal cord stimulation, 66% showed the complete synaptic pattern, 34% short latency or long latency components in isolation. The patterns obtained intracellularly corresponded well to discharge patterns recorded extracellularly. The results were essentially similar in control experiments performed on precollicularly decerebrated cats.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 652-652 
    ISSN: 1435-2451
    Keywords: Patients with organ failure ; Acid secretion ; Gastrin ; Acid inhibitory drugs ; Patienten mit Organinsuffizienz ; Säuresekretion ; Gastrin ; Säurehemmende Medikamente
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 9 Patienten auf der Intensivstation unserer Klinik mit einer oder mehrfacher Organinsuffizienz betrug die mittlere Säuresekretion/h unter Placebo 31 mEq, Cimetidin (8 × 200 mg i.v.) 7,5 mEq, Pirenzepin (4 × 10 mg i.v.) 22 mEq und Cimetidin + Pirenzepin 4,0 mEq. Alle Patienten zeigten eine Hypergastrinämie, die unter Placebo als auch unter der Medikamenten-Gabe bestehen blieb. Die erhöhten Gastrinwerte könnten einen Stimulus für die hohe Säuresekretion in diesen Streßulcus gefährdeten Patienten darstellen.
    Notes: Summary In nine patients at our intensive care unit with one or multiple organ failure, mean acid secretion/h was measured with placebo 31 mEq, cimetidine (8 × 200 mg IV) 7.5 mEq, pirenzepine (4 × 10 mg IV) 22 mEq and cimetidine + pirenzepine 4.0 mEq. All patients showed hypergastrinemia that was present under placebo as well as drug regimen. Increased gastrin might be one stimulus for increased acid secretion in these high-risk patients for stress ulceration.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1435-2451
    Keywords: Proximal gastric vagotomy ; Gastroduodenal ulcer ; Ten-year results ; Proximal selektive Vagotomie ; Gastroduodenales Ulcus ; 10-Jahres-Ergebnisse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir berichten über die 10-Jahres-Ergebnisse einer prospektiven multizentrischen Studie an 8 europäischen Kliniken (Basel, Bern, Düsseldorf, Erlangen, Freiburg, Krefeld, München Klinikum Grosshadern, Strassburg) zur Bewertung der proximal selektiven Vagotomie beim gastroduodenalen Ulcus. Die Nachuntersuchungsrate war 81%. Ergebnis:n symptomatisch total Visick Ulcustyp % Rezidivrate % 1 + II Ulcus duodeni524 13,6 20,4 88% Ulcus ventriculi 71 13,5 19,8 73% Ulcus pyloricum/praepyloricum 94 18,7 31,684% Kombinierte Ulcera 28 27,9 31,7 82%
    Notes: Summary We report the 10-year results of a prospective multicenter trial in eight European centers (Basel, Bern, Düsseldorf, Erlangen, Freiburg, Krefeld, München Klinikum Grosshadern, Strassburg) evaluating proximal gastric vagotomy for gastroduodenal ulcers. The follow-up rate was 81%. Results:n Symptomatic Total Visick Ulcer type recurrencerecurrence I + II (%) (%) Duodenal ulcer 524 13.6 20.488% Gastric ulcer 71 13.5 19.8 73% Pyloric/prepyloric ulcer 94 18.7 31.6 84% Combined ulcer 28 27.9 31.782%
    Type of Medium: Electronic Resource
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