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  • Electron microscopy  (3)
  • 12.20.Fv  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Megakaryoblastic micromegakaryocytic crisis in chronic myeloid leukemia (1985)
    Springer
    Annals of hematology 51 (1985), S. 275-285 
    Details
    ISSN: 1432-0584
    Keywords: Chronic myeloid leukemia ; Megakaryoblastic crisis ; Cytomechistry. Cytogenetics ; Cytophotometry ; Electron microscopy ; In vitro culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Atypical megakaryoblasts (MKB) or megakaryocytes (MK) are occasionally present in the peripheral blood during the terminal development of chronic myeloid leukemia (CML). We report on a 49-year-old female suffering from Ph1 chromosome-positive CML with typical megakaryoblastic transformation in the peripheral blood and in the bone marrow. The small “blasts” were at the most only slightly larger and were occasionally even smaller than lymphocytes but showed megakaryoblastic or atypical megakaryocytic differentiation. The cytoplasmic cytochemical pattern of the atypical megakaryocytic cells was identical to that of large atypical thrombocytes. Platelet peroxidase was detected upon electron-microscopic (EM) examination. Immunologic characterization disclosed the presence of MK-specific antigens. When cultured in vitro on agar, the blasts transformed spontaneously into large mature MK, exhibiting characteristic cytochemical and immunological patterns. Cytogenetic examination of peripheral blood showed severe abnormalities. The patient did not respond to therapy and died 3 months after manifestation of the blast crisis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320522
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Progressive liver failure in a patient with adult Niemann-Pick disease associated with generalized AL amyloidosis (1995)
    Springer
    Virchows Archiv 426 (1995), S. 635-639 
    Details
    ISSN: 1432-2307
    Keywords: Adult Niemann-Pick disease ; Generalized AL-amyloidosis ; Progressive liver failure ; Fibroblast culture ; Immunohistochemistry ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a case in which an adult form of Niemann-Pick disease (type B of NPD) was associated with a rapidly progressive generalized AL amyloidosis of kappa type. Both diagnosis were made by biopsy, the NPD by bone marrow biopsy and fibroblast culture, the amyloidosis by liver biopsy. Malignant non-Hodgkin lymphoma was not found. The patient, a 67-year-old woman, died from hepatic coma subsequent to a progressive liver failure. We discuss possible relations between the lysosomal storage disease and the development and rapid progression of amyloidosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00192120
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Evidence for a resonance in positron-electron scattering at 810 keV centre-of-mass Energy (1988)
    Springer
    The European physical journal 330 (1988), S. 173-181 
    Details
    ISSN: 1434-601X
    Keywords: 13.10.+q ; 12.20.Fv ; 14.80.Pb
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A monoenergetic positron (e +) beam (ΔT/T〈5·10−4) from the Stuttgart pelletron accelerator and a 4.6 mg/cm2 Be target has been employed to investigatee + e −scattering in the MeV region in a large solid angle with high statistics by means of a novel positionsensitive detector system. Superimposed on the Bhabha scattering, a structure has been found at ane + kinetic energy of 2263 keV (810 keV excitation energy in thee + e −rest frame). From the energy-integrated resonance cross-section of $$\sigma _{res} \cdot \Gamma _{res}^{e^ + e^ - } $$ ≅30 b·eV (c.m.) and the standard resonance cross-section we estimate partial resonance widths $$\Gamma _{res}^{e^ + e^ - } $$ ≅72 meV or 24 meV for total angular momenta J=0 or J=1, respectively. The structure, which has not been predicted within the framework of quantum electrodynamics, coincides with one of the sum energies of the correlatede + e −lines observed in heavy-ion collisions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01293393
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The significance of calcium antagonists in rat experimental tympanosclerosis (1987)
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1987), S. 382-386 
    Details
    ISSN: 1434-4726
    Keywords: Experimental tympanosclerosis ; Calcium antagonists ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of calcium antagonists in experimental tympanosclerosis following infection with Streptococcus pyogenes and vitamin D3 intoxication has been analyzed in a rat animal model. Compared with untreated animals, calcium antagonists exert a positive effect on the degenerative process and on secondary calcification in the subepithelial layer. This effect could be substantiated planimetrically.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00464647
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    Paper (German National Licenses)
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