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Digitale Medien

Binding of 16α-gitoxin and its 16-acetate to human serum albumin (1977)

Richter, M. ; Haustein, K. O.

Springer

European journal of clinical pharmacology 11 (1977), S. 459-461

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Details

ISSN: 1432-1041

Schlagwort(e): 16α-gitoxin ; 16-acetyl-16α-gitoxin ; ouabain ; digitoxin ; albumin binding

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary The binding of semi-synthetic (16α-gitoxin and its 16-acetate) and naturally occurring cardioactive glycosides (digitoxin, ouabain) to human serum albumin was studied using equilibrium dialysis, ultracentrifugation and gel filtration. 16α-gitoxin was 75% bound and its 16-acetate 95%. The percentage binding of digitoxin and ouabain was in good agreement with values reported in literature.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00562939

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