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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 38 (1996), S. 338-342 
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging ; Fluoride poisoning ; Ligaments ; Spinal cord compression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined four patients with fluorosis, presenting with compressive myelopathy, by MRI, using spin-echo and fast low-angle shot sequences. Cord compression due to ossification of the posterior longitudinal ligament (PLL) and ligamentum flavum (LF) was demonstrated in one and ossification of only the LF in one. Marrow signal was observed in the PLL and LF in all the patients on all pulse sequences. In patients with compressive myelopathy secondary to ossification of PLL and/or LF, fluorosis should be considered as a possible cuase, especially in endemic regions.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 38 (1996), S. 338-342 
    ISSN: 1432-1920
    Keywords: Key words Magnetic resonance imaging ; Fluoride poisoning ; Ligaments ; Spinal cord compression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined four patients with fluorosis, presenting with compressive myelopathy, by MRI, using spin-echo and fast low-angle shot sequences. Cord compression due to ossification of the posterior longitudinal ligament (PLL) and ligamentum flavum (LF) was demonstrated in one and ossification of only the LF in one. Marrow signal was observed in the PLL and LF in all the patients on all pulse sequences. In patients with compressive myelopathy secondary to ossification of PLL and/or LF, fluorosis should be considered as a possible cause, especially in endemic regions.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0749-1581
    Keywords: 1H NMR ; 13C NMR monomethyl/dimethyl 5α-androstan-3-ones ; Steroid ; Ring A conformation ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Ring A proton shifts and couplings and 13C shifts of all carbons are given for 17β-acetoxy-2α-methyl- and 17β-methoxy-2β-methyl-5α-androstan-3-one and 2,2-dimethyl-17β-methoxy-5α-androstan-3-one. It was concluded that the 2β-methyl derivative exists with ring A in a regular chair conformation while the 2β-methyl derivative exists with ring A in an inverted boat conformation with C-2 and C-5 at the bow/stern positions. The data for 2,2-dimethyl-17β-methoxy-5α-androstan-3-one suggest an equilibrium of these two conformers.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0749-1581
    Keywords: steroids ; 1H NMR ; 13C NMR ; coupling constants ; conformational analysis ; 1D TOCSY ; NOE ; cyclosteroids ; cyclopropanosteroids ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Proton and carbon NMR data are provided for 21 ring A and ring B cyclosteroids and cyclopropano (or methylene) steroids. Shift assignments were made using standard 2D NMR techniques, while ring A proton subspectra were extracted with a 1D TOCSY experiment. Coupling constants were obtained from iterative spin system simulation of these sub-spectra. Ring A conformations were determined from the two- and three-bond proton-proton couplings and NOE measurements. The utility and limitations of extended Karplus-type equations, the effect of cyclopropyl groups on vicinal and geminal couplings and cyclopropane-induced chemical shifts are discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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