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  • 25.70.Gh  (2)
  • 2-alkylbranched acids, esters and alcohols  (1)
  • 25.70.Pq  (1)
  • LD50 method
Materialart
Erscheinungszeitraum
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Tetrahedron: Asymmetry 2 (1991), S. 965-968 
    ISSN: 0957-4166
    Schlagwort(e): 2-alkylbranched acids, esters and alcohols ; chirality and odour ; flavour substances
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 350 (1995), S. 327-341 
    ISSN: 1434-601X
    Schlagwort(e): 25.70.Gh ; 25.70.Jj ; 25.70.Pq
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract In a multidetector experiment on 26 or 30 AMeV32S+58Ni, up to four coincident heavier or intermediate-mass fragments were observed. One of these occasionally has the characteristics of a projectile-like fragment, up to three may be attributed to the decay of the heavy reaction product. Taking the velocity of the fragments as a measure of the heavy-product excitation energy, one finds evaporation, fission and multifragmentation to follow one another with rising excitation. Model simulations of sequential decay with up to two binary fissions and, alternatively, of simultaneous statistical multifragmentation were performed for comparison with experimental distributions of mass, velocity and (for events with three slow intermediate-mass fragments) relative azimuthal angle. Though in the three-fragment events indications of simultaneous multifragmentation are present, the sequential binary decay predominates. Evaporated protons and α particles detected in coincidence have a mean multiplicity growing with excitation energy, while the temperature governing the spectra has a plateau with a value of about 5.5 MeV.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    ISSN: 1434-601X
    Schlagwort(e): 25.70.Gh ; 25.70.Jj ; 25.70.Lm
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract For the violent collisions of 27 MeV/nucleon40Ar with Ag, coincidence measurements have been made between heavy residues and intermediate mass fragments (3≦Z≦14) or light charged particles. From the analysis of the correlation between heavy residues (mass and velocity) and intermediate mass fragments, the main characteristics of the dominant mechanisms, fusion and partially damped collisions preceded or accompanied by a preequilibrium emission, are presented. Balances concerning mean values of parallel linear momentum, mass and atomic number, are established and confirm that a complete description of violent collisions was obtained. Then thermalization is discussed, first in terms of excitation energies derived from kinematics between heavy residues and intermediate mass fragments, and secondly in terms of initial temperature estimates derived from light charged particle spectra. Very hot nuclei (T⋍5.7–6.6 MeV) are produced over a large impact parameter range from very central collisions to medium peripheral ones. Various experimental results are compared to predictions obtained with semi-classical calculations (Landau-Vlasov equation). From their good agreement one may conclude that, depending on the impact parameter, thermal equilibrium is achieved within 4–10×10−22 s.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Archives of toxicology 51 (1982), S. 197-220 
    ISSN: 1432-0738
    Schlagwort(e): Acute toxicity ; LD50 method
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract 170 acute toxicity determinations, carried out in rats, mice, and guinea pigs after oral and parenteral administration during the past 5 years, using 5 ♂/5 ♀ animals per dose, were evaluated with respect to the possibility of a reduction of animals necessary for obtaining LD50 values with limits of confidence. Calculations were performed on existing data; no additional animal experiments were initiated for the purpose of this paper. For the majority of substances 3 ♂/3 ♀ animals per dose would have sufficed for the determination of a LD50 value with limits of confidence. Even when using 2 ♂/2 ♀ animals per dose, in most cases sufficently acceptable LD50 values can be determined, if the period of observation — conventionally 4 weeks — would be doubled. Using this procedure, 75% of the animals could be saved. The reduced number of animals and the labor saved thereby would allow for a more individualized observation of single animals thus optimizing the evaluation of acute toxicity testing.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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