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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 149 (1990), S. 393-395 
    ISSN: 1432-1076
    Keywords: Age dependence ; Detoxification capacity ; Liver-Stable isotopes ; 15N urine test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The [15N]methacetin urine test was used to study human O-demethylase activities to characterize the maturation of hepatic detoxification capacity. The study involved 43 healthy subjects aged 1 day−47 years. The urinary15N elimination rates were measured following oral administrations of an aqueous [15N]methacetin solution. Age-dependent normal values of hepatic drug elimination capacity were established. Parameters were the15N elimination half-life and cumulative elimination of the15N dose as a percentage over a 9 h period. The maximum elimination rate (% dose/h) and peak time can give additional information. The15N method is a simple, noninvasive and non-radioactive liver function test avoiding disadvantages of14C and13C breath tests. The [15N]methacetin test is suitable and useful in studying the hepatic development at birth and pathological changes of the microsomal detoxification capacity in early childhood.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-601X
    Keywords: 21.10.Re ; 21.10.Tg ; 27.60+j
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The mean lifetimes of the lower spin states of the superdeformed band in133Nd have been measured with the coincidence recoil distance method. The reaction used to populate the band was105Pd (32S, 2p2n)133Nd at a beam energy of 152 MeV, and the gamma-rays were detected with the POLYTESSA array. The differential decay curve method was used to analyse the data and transition quadrupole moments,Q 0, were extracted from the measured lifetimes. The results obtained from the three lowest transitions in the superdeformed band are:Q 0=6.3±0.9 eb (21+/2→17+/2),Q 0=6.7±1.1 eb (25+/2→21+/2) andQ 0〉5.0 eb (29+/2→25+/2). These results are consistent with previous results for the high spin members of the band, and are compared to theoretical calculations of total routhian surfaces. The calculation of reduced transition probabilities for the transitions that feed out of the band, allows the effect of hindrance due to K-forbiddenness to be investigated.
    Type of Medium: Electronic Resource
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