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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 123 (1997), S. 69-70 
    ISSN: 1432-1335
    Keywords: BRCA1 ; Mutations ; Phenotype
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract More than 100 mutations have been described for the breast-cancer-susceptibility geneBRCA1. The paper describes phenotypical aspects of three selected mutations located at the beginning, in the middle, and at the end of the gene. A remarkable decrease of the age of diagnosis of the mammary carcinoma is observed with increasing length of the putative gene product, combined with greater severity of the disease.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 339 (1991), S. 435-444 
    ISSN: 1434-601X
    Keywords: 21.60−n ; 23.40−s ; 23.40.Hc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Nuclear matrix elements of the two-neutrino and neutrinolessββ decays of48Ca(0 g.s. + )→48Ti(0 g.s. + ) are calculated by shell model and QRPA. The two-neutrino matrix elementM GT 2v is rather reliably evaluated in the QRPA approach by a careful fit of the particle-particle interaction strength in the 1+ channel, which governs the spinisospin ground-state correlations. The shell-model value ofM GT 2v depends not only on the 1+ interaction but largely on the pairing and quadrupole interactions. Concerning the neutrinoless-mode nuclear matrix elements, the shell model gives generally smaller values than the QRPA. A detailed analysis indicates that the discrepancies originate mainly from the truncation of shell-model configurations (fp-space). The QRPA calculation in a larger model space well takes into account transitions from/to single-particle orbits far from the Fermi surface, and those transitions give rise to sizable contributions because of large momentum transfers due to the exchange of a virtual neutrino.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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