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  • Chemistry  (4)
  • 21.60.Ev
  • Intraventrikuläre Blutung
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 105 (1993), S. 243-245 
    ISSN: 1437-1596
    Keywords: Intraventricular haemorrhage ; Head injury ; Traumatic subarachnoid haemorrhage ; Intraventrikuläre Blutung ; Kopftrauma ; Traumatische Subarachnoidalblutung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Der Fall eines 26 Jahre alten Mannes wird beschrieben, welcher nach einer Episode von Traumen eine tödliche intraventrikuläre Hirnblutung erlitt. Bei der Obduktion wurde nach dem ersten Eindruck eine traumatische Subarachnoidalblutung vermutet, und die anfängliche Untersuchung war daher auf die Strukturen des Halses und auf die Vertebralarterien gerichtet, jedoch mit negativen Resultaten. Die Sektion des fixierten Gehirns zeigte eine massive intraventrikuläre Blutung mit sekundärer Beteiligung des Subarachnoidalraums und Ausbreitung in das Hirnparenchym. Keine Blutungsquellen oder natürliche Erkrankungen der Hirngefäße konnten gefunden werden. Die praktischen Aspekte der Diagnose und der vorsichtige Ansatz, welcher notwendig ist, um Subarachnoidalblutungen zu interpretieren, werden betont. Die Bedeutung der intraventrikulären Blutung nach Trauma ist mit der Einführung der Computertomographie offensichtlicher geworden. Die Implikationen dieses und ähnlicher Fälle werden bedacht.
    Notes: Summary A case of a 26-year-old man who suffered a fatal intraventricular cerebral haemorrhage following an episode of trauma is described. The initial appearance at necropsy suggested a traumatic subarachnoid haemorrhage and initial investigation was directed towards the anterior neck structures and the vertebral arteries with negative results. Dissection of the fixed brain showed a massive intraventricular bleed with secondary involvement of the subarachnoid space and dissection into the cerebral parenchyma. No bleeding points or natural disease of the cerebral vessels could be identified. The practical aspects of diagnosis and the cautious approach necessary in interpreting subarachnoid bleeding is emphasised. The significance of intraventricular haemorrhage following trauma has become more apparent with the advent of computed tomographic scanning. The implications for this and similar cases are considered.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-601X
    Keywords: 21.60.Ev ; 29.30.Kv ; 27.70.+q
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract High spin states of175, 176Pt have been populated in144Sm(35Cl,pxn) reactions at beam energies of 175–185 MeV. In-beamγ-ray spectroscopic techniques using the ESSA30 spectrometer array were adopted. Levels up to spin 26 in176Pt and tentatively up to spin 45/2 in175Pt have been identified. The data are interpreted within the framework of Cranked Shell Model calculations using the deformed Woods-Saxon potential and including monopole pairing.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 9 (1970), S. 445-457 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The change in apparent molal volume φ of DNA on thermal denaturation in carbonate buffer at pH 11.0 has been determined by the dilatometric method. It was found that φ increases sigmoidally during the helix-coil transition. Several methods, including a colorimetric technique that closely simulates the conditions used in the dilatometric experiments, were employed to estimate the protons lost by the DNA during the transition. These measurements indicated that the extent of the proton loss depends on the counterion present, increasing in the order Li+ 〈 Na+ 〈 K+ 〈 Cs+. The major part of the volume changes observed during the denaturation is due to the volume changes expected to accompany the transfer of protons from the bases guanine and thym ne to carbonate ions. As has been previously reported for the denaturation of DNA at neutral pH, the volume change directly due to the change in shape of the polymer molecules is so small as to be experimentally undetectable.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 7 (1969), S. 527-537 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Dilatometric measurements were made to determine the change in apparent specific volume ϕ of DNA resulting from thermal denaturation in neutral solution, ϕ increased continuously with temperature in the range 10-85°C. No deviations from a monotonically rising curve were observed in the ϕ versus temperature profile in the region of the melting temperature. The results are interpreted in terms of a partial loss of the preferentially bound DNA hydration shell. The nature of the well known buoyant density difference between native and denatured DNA was investigated by evaluating the densities in a series of cesium salt gradients at constant temperature. Extrapolation of the results to zero water activity indicates that the partial specific volumes of anhydrous native and denatured DNA are equal. The density difference at nonzero water activities is attributed to decreased hydration in the denatured state. The absence of a related change in ϕ accompanying the denaturation in the dilatometric experiments suggests that the probable volume change associated with loss of bound water during denaturation is accompanied by other compensatory volume effects. The possible nature of these volume effects is discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0449-2986
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0721-3115
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The appearance of a significant deuterium isotope effect during the combustion of the solid HMX compound verifies that the chemical reaction kinetics is a major contributor in determining the experimentally observed or global burn rate. Burn rate comparison of HMX and its deuterium labeled HMX-d8 analogue reveals a primary kinetic deuterium isotope effect (1° KDIE) at 500 psig (3.55 MPa) and l000 psig (6.99 MPa) pressures and selectively identifies covalent carbon-hydrogen bond rupture as the mechanistic step which ultimately controls the HMX bum rate under the static combustion conditions of this experiment. The 1° KDIE value further suggests the rate-limiting C—H bond rupture occurs during the solid state HMX decomposition/deflagration portion of the overall combustion event and is supported by other independently published studies. A possible anomalous KDIE result at 1500 psig (10.4 MPa) is addressed. This condensed phase KDIE approach illustrates a direct link between lower temperature/pressure thermal decomposition and deflagration processes and their potential applicability to the combustion regime. Most importantly, a new general method is demonstrated for mechanistic combustion investigations which selectively permits an in-situ identification of the compound's burn rate-controlling step.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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