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  • 25.70Jj  (1)
  • Antibiotic treatment  (1)
  • Bioimpedance  (1)
  • Body temperature  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 18 (1992), S. 322-326 
    ISSN: 1432-1238
    Keywords: Body water ; Bioimpedance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To evaluate the relationship between changes in body bioelectrical impedance (BI) at 0.5, 50 and kHz and the changes in body weight, as an index of total body water changes, in acutely ill surgical patients during the rapid infusion of isotonic saline solution.Design: Prospective clinical study.Setting: Multidisciplinary surgical ICU in a university hospital.Patients: Twelve male patients treated for acute surgical illness (multiple trauman=5, major surgeryn=7). Selection criteria: stable cardiovascular parameters, normal cardiac function, signs of hypovolemia (CVP≤5 mmHg, urine ouput 〈1 ml/kg×h).Interventions: After baseline measurements, a 60 min fluid challenge test was performed with normal saline solution, 0.25 ml/kg.Measurements and results: Body weight (platform digital scale), total body impedance (four-surface electrode technique; measurements at 0.5, 50 and 100 kHz) and urine output. Fluid retention induced a progressive decrease in BI at 0.5, 50 and 100 kHz, but the changes were significant for BI 0.5 and BI 100 only, from 40 min after the beginning of the fluid therapy onwards. There was a significant negative correlation between changes in water retention and BI 0.5, with individual correlation coefficients ranging from −0.72 to 0.95 (p〈0.01–0.0001). The slopes of the regression lines indicated that for each kg of water change, there was a mean decrease in BI of 18 ohm, but a substantial inter-individual variability was noted.Conclusion: BI measured at low frequency can represent a valuable index of acute changes in body water in a group of surgical patients but not in a given individual
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1076
    Keywords: Key words Cystic fibrosis ; Resting energy expenditure ; Antibiotic treatment ; TNF-α
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cystic fibrosis (CF) patients often present with malnutrition which may partly be due to increased resting energy expenditure (REE) secondary to inflammation. Both REE and tumour necrosis factor-alpha (TNF-α), as other markers of inflammation, are elevated during respiratory exacerbations and decrease after antibiotic treatment. However, the effect of antibiotic therapy on REE and inflammation in patients without respiratory exacerbation is not known. The aim of our study was to determine the effect of such an elective antibiotic therapy on REE, TNF-α, and other serum markers of inflammation. Twelve CF patients 5F/7M, age 15.9 ± 6.1 years, weight for height ratio 89 ± 8% without clinically obvious exacerbation and treated by intravenous antibiotics were studied. Both before (D0) and after (D14) treatment, pulmonary function tests were performed. REE was measured by indirect calorimetry and blood taken to measure inflammation parameters. Body weight increased by 1.1 kg from D0 to D14 (P 〈 0.001), composed of 0.3 kg fat mass and 0.8 kg fat-free mass (FFM). The forced expiratory volume at 1 s increased from 43 ± 15% of predicted at D0 to 51 ± 15% of predicted at D14 (P 〈 0.01). Mean REE was 41.1 ± 7.6 kcal/kg FFM per day at D0 and did not change significantly at D14 (40.6 ± 8.5 kcal/kg FFM per day). Serum markers of inflammation decreased from D0 to D14: C-reactive protein 17 ± 17 mg/l to 4 ± 7 mg/l (P 〈 0.05), elastase 62 ± 29 μg/l to 45 ± 18 μg/l (P 〈 0.02), orosomucoid acid 1.25 ± 0.11 g/l to 0.80 ± 0.15 g/l (P 〈 0.001), and TNF-α 37 ± 14 pg/ml to 29 ± 6 pg/ml (P = 0.05). Individual values showed a correlation between changes in REE and in TNF-α (P 〈 0.02). Conclusion The contribution of inflammation to energy expenditure is possible but appears to be minimal in cystic fibrosis patients treated by antibiotics on a regular basis in the absence of clinically obvious exacerbation.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1439-6327
    Keywords: Menstrual cycle ; Sweating ; Body temperature ; Thermoregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The whole body sweating response was measured at rest in eight women during the follicular (F) and the luteal (L) phases of the menstrual cycle. Subjects were exposed for 30-min to neutral (N) environmental conditions [ambient temperature (T a) 28°C] and then for 90-min to warm (W) environmental conditions (Ta, 35°C) in a direct calorimeter. At the end of the N exposure, tympanic temperature (T ty) was 0.18 (SEM 0.06)°C higher in the L than in the F phase (P〈0.05), whereas mean skin temperature ( $$\bar T_{{\text{sk}}}$$ ) was unchanged. During W exposure, the time to the onset of sweating as well as the concomitant increase in body heat content were similar in both phases. At the onset of sweating, the tympanic threshold temperature (T ty, thresh) was higher in the L phase [37.18 (SEM 0.08)°C] than in the F phase [36.95 (SEM 0.07)°C;P〈0.01]. The magnitude of the shift inT ty, thresh [0.23 (SEM 0.07)°C] was similar to the L-F difference inT ty observed at the end of the N exposure. The mean skin threshold temperature was not statistically different between the two phases. The slope of the relationship between sweating rate andT ty was similar in F and L. It was concluded that the internal set point temperature of resting women exposed to warm environmental conditions shifted to a higher value during the L phase compared to the F phase of the menstrual cycle; and that the magnitude of the shift corresponded to the difference in internal temperature observed in neutral environmental conditions between the two phases.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-601X
    Keywords: 25.70z ; 25.70Jj ; 25.70Np
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The light charged particles emitted in the40Ar+68Zn reaction performed at 14.6, 19.6 and 35 MeV/nucleon have been studied inclusively. The energy spectra have been analysed in terms of preequilibrium emission, moving source and coalescence models. A complete coherence between the present data and those obtained separately from heavy fragment studies is achieved. These data are consistent with the onset of projectile fragmentation between 20 and 35 MeV/nucleon correlated with the formation of a highly excited region of the nuclear system inducing light particle emission. The other sources of light particles can be interpreted as statistical and sequential decay of the quasi projectile.
    Type of Medium: Electronic Resource
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