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  • 27.40.+ z  (1)
  •  Liver  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Binding of Cu to metallothionein in tissues of the LEC rat with inherited abnormal copper accumulation (1997)
    Springer
    Archives of toxicology 71 (1997), S. 340-343 
    Details
    ISSN: 1432-0738
    Keywords: Key words LEC rat  ;  Copper  ;  Metallothionein  ;   Hepatitis  ;  Liver
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Long-Evans Cinnamon (LEC) rats aged 16 ± 4 weeks with histopathological alterations of liver and kidney, exhibited elevated Cu levels in liver, kidney and spleen which were 52, 27 and 5 times higher than those of the respective tissues of age-matched Wistar rats. About 61% of hepatic and about 38% of renal Cu was recovered in the cytosolic fraction. Metallothionein (MT) levels were found to correlate with the cytosolic Cu concentrations in liver and kidney. According to differential MT analysis, about 68 and 82% of hepatic and renal MT was loaded with Cu. The portion of MT which binds Cu was negatively correlated with the ratio of cytosolic Zn/Cu in all organs investigated. Despite high MT levels and the high percentage of Cu binding to MT, particularly in liver and kidney, considerable amounts of Cu remained unbound to MT. This non-MT bound Cu showed good correlation with the total cytosolic Cu content, and might play a crucial role in the pathogenesis of Cu toxicosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002040050396
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  • 2
    Electronic Resource
    Electronic Resource
    Complete spectroscopy of51,52V via the50,51V(n, γ) reactions (1991)
    Springer
    The European physical journal 338 (1991), S. 371-387 
    Details
    ISSN: 1434-601X
    Keywords: 21.10.Ma ; 23.20.Lv ; 25.40.Lw ; 27.40.+ z
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The gamma-ray spectra emitted after thermal neutron capture in highly enriched50V andnatV targets have been studied using in-pile targets at the ILL high flux reactor and pair and germanium detectors. The neutron binding energies in51V and52V were determined to beB n (51V)=11051.11(17) keV andB n (52V)=7311.22(26) keV. The thermal neutron capture cross-section in50V was measured to be 21 −2 +4 b. From 724 lines attributed to51V, 330 transitions, comprising 90% of theγ-ray flux, were placed into the level scheme. Fifty-nine primary dipole transitions from the 11/2+ or 13/2+ capture states in51V were established from which the E1 strength distribution was deduced. The energy scaling of these primary transitions was found to follow the E1-giant dipole resonance dominance. Many new levels were established; a number of states proposed in previous (d,p) and (n,γ) work were confirmed from their primary population and decaying secondary radiations. The density of levels in the high spin (9/2≦I≦15/2) region was parametrized with the Fermi gas model. The spin distributions of51V were analyzed and a spin cut-off parameter σ=2.8 (3) was deduced. — A nearly complete level scheme of52V up to 3.5 MeV excitation and similar results concerning the level density and the primary γ-ray spectrum were obtained in the51V (n, γ)52V study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01295765
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    Paper (German National Licenses)
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