ISSN:
1420-9071
Keywords:
Cyclosporin A
;
cellular immunity
;
Streptozocin
;
insulitis
;
diabetes mellitus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Cyclosporin A (CYA), when administered to CD-1 mice treated with a subdiabetogenic dose of Streptozocin (STZ), exacerbated the STZ-induced insulitis and elevated the plasma glucose levels, parallel to a reduction of the insulin content of the pancreas. The possible mechanisms of CYA-mediated aggravation of STZ-induced diabetes are discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01945570
Permalink