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  • 34.50.Pi  (2)
  • Chronic intrahepatic cholestasis  (2)
  • Ileumresektion  (2)
  • Quantification  (2)
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Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Biliary lipid metabolism in children with chronic intrahepatic cholestasis (1984)
    Springer
    European journal of pediatrics 143 (1984), S. 35-40 
    Details
    ISSN: 1432-1076
    Keywords: Chronic intrahepatic cholestasis ; Biliary lipid composition ; Bile acids ; Gallstones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Biliary lipid composition, standard liver function tests, serum lipids and faecal fat excretion were studied in 15 children with chronic intrahepatic cholestasis (severe intrahepatic cholestasis, n=6; paucity of intralobular bile ducts, n=4; benign recurrent cholestasis, n=5) and compared to 15 children without gastrointestinal diseases. Severe and benign intrahepatic cholestasis were associated with normal or moderately elevated serum lipids. Biliary lipid concentrations were extremely reduced, bile acid concentrations were below the critical micellar concentration. This may account for the high incidence of gallstone formation in these patients. Remission periods in patients with benign recurrent cholestasis were not followed by complete normalisation of biliary lipid concentrations, indicating a primary defect in hepatic excretory function. Children with paucity of intralobular bile ducts showed markedly increased serum lipids, but only a two-fold reduction in biliary lipid concentrations. Cholic acid was the predominant bile acid in bile of all cholestatic children even during remission. Neither increased levels of monohydroxy bile acids nor unusual bile acids could be identified in notable amounts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442745
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of phenobarbital on biliary lipid metabolism in children with chronic intrahepatic cholestasis (1984)
    Springer
    European journal of pediatrics 143 (1984), S. 41-44 
    Details
    ISSN: 1432-1076
    Keywords: Chronic intrahepatic cholestasis ; Biliary lipid composition ; Bile acids ; Phenobarbital
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of phenobarbital (5.4–7.5 mg/kg body weight) for 14 days were studied in four children with severe intrahepatic cholestasis (group I) and in four with a syndromatic type of paucity of intralobular bile ducts (group II). Phenobarbital administration resulted in a moderate improvement of pruritus in all patients. There was a significant decrease of bilirubin in serum (group I: from 4.8 to 2.7 mg/dl; group II: from 6.1 to 2.1 mg/dl); total bile acids (group I: from 416 to 337 μmol/l; group II: from 156 to 123 μmol/l) and cholesterol (group I: from 248 to 207 mg/dl; group II: from 351 to 292 mg/dl). Alkaline phosphatase activity increased from 929 to 1126 U/l in group I and from 1751 to 2360 U/l in group II. SGOT and SGPT activities remained unchanged in both groups. In group I total biliary lipid concentration and bile acid output increased from 0.09 to 0.17 g/dl and from 3.9 to 7.2 μmol/kg per 30 min, respectively. Molar percentages of cholesterol, phospholipids and bile acids in bile remained unchanged. In group II total lipid concentrations and bile acid output increased from 1.62 to 2.0 g/dl and from 27.8 to 39.1 μmol/kg per 30 min, respectively. The molar percentage of cholesterol decreased from 5.6 to 3.5 mol%. The present results indicate that short term administration of phenobarbital has only minimal effects on biliary lipid metabolism in children with chronic intrahepatic cholestasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442746
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  • 3
    Electronic Resource
    Electronic Resource
    Lebercirrhose und duodenogastrischer Reflux —Zum Problem des hepatogenen Ulcus (1983)
    Springer
    Langenbeck's archives of surgery 360 (1983), S. 109-118 
    Details
    ISSN: 1435-2451
    Keywords: Duodenogastric reflux ; Quantification ; Liver cirrhosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der duodenogastrische Reflux wurde quantitativ bei Patienten mit histologisch nachgewiesener Lebercirrhose und magen- und lebergesunden Kontrollpersonen bestimmt. Die Bestimmung des duodenogastrischen Refluxes erfolgte nach dem Gallemarkerprinzip unter Verwendung des Tricarbocyanin-Farbstoffes Indocyaningreen (ICG). Die intragastrale Konzentration von ICG wurde nach Ausheberung des Magensaftes über eine Magensonde photometrisch gemessen und der duodenogastrische Reflux in Prozent der infundierten bzw. biliär sezernierten ICG-Menge berechnet. Bromthalein wurde als zusätzlicher Marker benutzt, um eine Kontrolle über die Vollständigkeit der Magensaftelimination zu erreichen. Insgesamt wurden 15 Patienten mit Lebercirrhose und 6 magen- und lebergesunde Kontrollpersonen untersucht. Die Patienten mit Lebercirrhose wiesen einen Reflux von 2,85% ± 0,76%, die magen- und lebergesunden Kontrollpersonen (n = 6) einen Reflux von 0,45 ± 0,39 % auf. Der Unterschiediststatistischsignificant(P 〈 0,05). Die Bromthaleinaspiration betrug bei allen Lebercirrhotikern 87,95 ± 2,78 % der infundierten Menge.
    Notes: Summary Patients suffering from liver cirrhosis and patients showing no signs of liver or stomach disease (control group) were quantitatively examined for duodenogastric reflux. The duodenogastric reflux was measured by means of bile tracers. The bile tracer used in this study was the tricarbocyanin dye indocyningreen (ICG). The intra-gastric concentration of ICG was photometrically measured after gastric acid was suctioned through a stomach tube. The duodenogastric reflux was calculated in percent in terms of the infused and the biliary secreted ICG amount respectively. Bromthalein was used as an additional tracer in order to control the efficiency of peptic acid removal. A total of 15 patients suffering from liver cirrhosis and 6 patients who showed no signs of stomach or liver disease (control group) were examined. The patients with liver disease showed a reflux of 2.85% ± 0.76%, the control group (n = 6) showed a reflux of 0.45% ± 0.39%. The difference is statistically significant (P 〈 0.05). Bromthalein aspiration by all patients with liver cirrhosis was 87.95 ± 2.78% of the amount infused.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01254919
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  • 4
    Electronic Resource
    Electronic Resource
    175. Postoperatives Beschwerdebild nach Dünndarmresektionen (1981)
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 549-549 
    Details
    ISSN: 1435-2451
    Keywords: Resection of the ileum ; Postoperative symptomes ; Ileumresektion ; Postoperatives Beschwerdebild
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Zur Erfassung des klinischen Beschwerdebildes dünndarmresezierter Patienten wurden von 197 Patienten mit isolierter Dünndarmresektion aus den Jahren 1958-1978 der Chirurgischen Universitäts Klinik Bonn 68 Patienten befragt und die Ergebnisse ausgewertet. Von diesen wurde bei 14 Patienten weniger als 30 cm Ileum reseziert, bei 21 Patienten 30- 80 cm, bei 19 Patienten 80-150 cm und bei 9 Patienten mehr als 150 cm. Bei 5 Patienten wurden 80 cm Jejunum reseziert. 53 (77,9%) der befragten Patienten gaben z. Z. der Entlassung Durchfälle an. Bei 16 Patienten (23,5%) trat postoperativ keine Besserung ein, bei 26 Patiente (38,2%) dauerte die Adaptation 3 Monate bis zu 1 Jahr. Zwischen Resektatlänge und Stuhlfrequenz sowie allgemeinem Beschwerdebild fand sich bei fast allen Gruppen eine Korrelation.
    Notes: Summary To document the clinical symptoms after partial resection of the small intestine 68 patients of a total of 197 patients operated during the period of 1958-1978, Department of Surgery, University of Bonn, were evaluated for their postoperative symptoms. Of the 68 patients 14 had a resection of less than 30 cm of the ileum, 21 patients of 30–80cm, and 9 more than 150cm. Five patients had undergone a resection of 80 cm of jejunum. Of these patients 53 (78%) had diarrhea at the time of discharge from the hospital. A normalisation of the bowel movement appeared after 3 to 12 months in 26 patients (38%),16 patients (24%) experienced no improvement at all. A correlation between the length of intestinal resection and requency of bowel movements as well as general symptoms was found in all groups of patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01287005
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  • 5
    Electronic Resource
    Electronic Resource
    121. Ursachen für das gehäufte Auftreten von Cholesteringallensteinen nach Resektion des terminalen Deums (1982)
    Springer
    Langenbeck's archives of surgery 358 (1982), S. 471-471 
    Details
    ISSN: 1435-2451
    Keywords: Ileal resection ; Biliary secretion ; Cholesterol gallstone formation ; Ileumresektion ; biliäre Sekretion ; Cholesteringallensteinbildung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Patienten mit Resektion des terminalen Ileums weisen eine erhöhte Incidenz von Cholesteringallensteinen auf. Zur Aufklärung des Mechanismus der Steinbildung wurde bei 5 Patienten mit Ileumresektion (mehr als 120 cm) und bei 5 Kontrollpersonen die biliäre Lipidsekretion über 24 h gemessen. Die biliäre Sekretion von Gallensäuren (GS), Phospholipiden (PL) und Cholesterin (CH) war bei den resezierten Patienten um 52 %, 53 % bzw. 47 % erniedrigt. Die Reduktion der CH-Sekretion war nicht so ausgeprägt wie die von GS und PL. Aus diesem Grunde war die Galle bei Ileumresezierten 14 h am Tag mit CH übersättigt, im Gegensatz zu 7h bei den Kontrollpersonen (p 〈 0,0s1).
    Notes: Summary Patients with resection of the ileum are at increased risk of forming cholesterol gallstones. In order to investigate the underlying mechanism of stone formation, biliary lipid secretion was measured for 24 h in five patients after ileal resection (more than 120 cm) and five controls. The biliary secretion of bile acid (BA), phospholipids (PL), and cholesterol (CH) in ileal resected patients was reduced by 52%, 53%, and 47%, respectively. The reduction in cholesterol secretion rate was not as much as that of BA and Pl. As a result, the bile in patients with ideal resection was supersaturated with CH for 14h in contrast to 7 h in control subjects (p 〈 0.01).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271868
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  • 6
    Electronic Resource
    Electronic Resource
    Quantitative Bestimmung des duodenogastrischen Refluxes bei verschiedenen Magenresektionsverfahren (1981)
    Springer
    Langenbeck's archives of surgery 354 (1981), S. 273-279 
    Details
    ISSN: 1435-2451
    Keywords: Duodenogastric reflux ; Quantification ; Gastric resection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der duoenogastrische Reflux wurde quantitativ bei den klassischen Magenresektionsverfahren (Billroth II — mit und ohne Enteroanastomose, Billroth I), sowie bei Magengesunden bestimmt. Insgesamt wurden 43 Magenresezierte und 6 Magengesunde untersucht. Die B II-Resezierten ohne Braunsche Enteroanastomose (n = 10) wiesen einen Reflux von 50,4 ± 4,1 % (SEM) der während der Untersuchung sezernierten Gallenmenge auf. Bei den B II-Resezierten mit Braunscher Enteroanastomose (n = 15) betrug der Reflux 21,5 ± 3,7 % (SEM), bei den B I-Resezierten (n =17) 23,1 ± 3,5 (SEM). Die magengesunden Kontrollpersonen (n = 6) wiesen einen Reflux von 0,5 ± 0,4% (SEM) auf.
    Notes: Summary The duodenogastric reflux was measured quantitatively in patients with classic gastric resections (Billroth I, Billroth II with and without enteroanastomosis) as well as in patients without gastric operations. A total of 43 patients with gastric resection and 6 without gastric operation were studied. Patients operated according to B II without Braun's enteroanastomosis (n = 10) had a bile reflux of 50.4 ± 4.1 % (SEM) during the study. Patients having been operated according to B II- with Braun's-enteroanastomosis (n = 15) and those having undergone B I-operation (n = 17) had a duodenogastric reflux of 21.5 ± 3.7 % (SEM) and 23.1 ± 3.5 % (SEM), respectively. In 6 control subjects without gastric operation bile reflux into the stomach averaged 0.5 ± 0.4 % (SEM).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271337
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  • 7
    Electronic Resource
    Electronic Resource
    The effect of vibrational bond stretching on rotational inelastic electron-molecule scattering (1988)
    Springer
    The European physical journal 10 (1988), S. 247-252 
    Details
    ISSN: 1434-6079
    Keywords: 34.50.Ez ; 34.50.Pi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Differential cross sections for state-to-state rotationally inelastic electron-Na2 scattering, with the molecule being in the vibrational levelv′'=31, are measured at a collision energy of 150 eV. Angular momentum transfer of up to Δj=26 is observed, which is even more than previously obtained for the vibrational ground statev′'=0. Good agreement is found with theoretical results from a spectator scattering model. This work, in general, elucidates the role of vibrational excitation in collision dynamics under vibrationally sudden conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01384859
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  • 8
    Electronic Resource
    Electronic Resource
    Rotational excitation by electron impact: a state selective study using laser-induced fluorescence (1990)
    Springer
    The European physical journal 16 (1990), S. 207-217 
    Details
    ISSN: 1434-6079
    Keywords: 34.80.Gs ; 34.50.Ez ; 34.50.Pi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Angularly resolved pure rotational excitation of sodium dimers by intermediate energy electrons (150 to 300 eV) is studied using laser state selection technique, under nonresonant collision conditions. The experimental procedure, which is new to electron scattering, is described in detail. The experimental data show large rotational transitions and rotational rainbow structures. The relative cross sections agree well with the close coupling calculations and also with the spectator model predictions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01437334
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