ZIB

Treffer pro Seite

Treffer 1 - 1 | 1 Treffer

Sortierung

Digitale Medien

Physostigmine restores3H-acetylcholine efflux from Alzheimer brain slices to normal level (1986)

Nilsson, Lena ; Nordberg, Agneta ; Hardy, J. ; [weitere]

Springer

Journal of neural transmission 67 (1986), S. 275-285

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1435-1463

Schlagwort(e): Post mortem ; 3H-acetylcholine ; release ; physostigmine

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary A technique was developed, which made it possible to study thein vitro release of3H-acetylcholine (3H-ACh) from human post mortem brain tissue, collected with short post-mortem delay (2,5–22 hours), both from controls and patients with Alzheimer's disease (AD/SDAT). The tritium (3H) release was investigated during potassium stimulation, and AD/SDAT cortical slices were found to release a decreased amount of3H compared to control brain slices. Physostigmine, 10−5 and 10−4 M, has no significant effect on the release of3H from control slices, while physostigmine 10−4 M increased the evoked release from AD/SDAT brain slices over threefold, nearly to the control level.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01243353

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 1 | 1 Treffer