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  • 1
    Electronic Resource
    Electronic Resource
    A Trifluoroacetylation-Fluorine-19 Nuclear Magnetic Resonance Technique for Characterization of Hydroxyl Groups in Poly(Propylene Oxides). (1966)
    s.l. : American Chemical Society
    Analytical chemistry 38 (1966), S. 1063-1065 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60240a028
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  • 2
    Electronic Resource
    Electronic Resource
    Electron Spin Resonance and Isotopic Exchange Studies in the Tritium-Polystyrene Fluff System1 (1962)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 84 (1962), S. 2831-2832 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00873a041
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  • 3
    Electronic Resource
    Electronic Resource
    Distinctive neuropathology revealed by α-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p (2000)
    Springer
    Acta neuropathologica 99 (2000), S. 663-672 
    Details
    ISSN: 1432-0533
    Keywords: Key words Dementia ; Lewy body ; Neuropathology ; Synuclein ; Western blotting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The identification of the α-synuclein gene on chromosome 4q as a locus for familial Lewy-body parkinsonism and of α-synuclein as a component of Lewy bodies has heralded a new era in the study of Parkinson’s disease. We have identified a large family with Lewy body parkinsonism linked to a novel locus on chromosome 4p15 that does not have a mutation in the α-synuclein gene. Here we report the clinical and neuropathological findings in an individual from this family and describe unusual high molecular weight α-synuclein-immunoreactive proteins in brain homogenates from brain regions with the most marked neuropathology. Distinctive histopathology was revealed with α-synuclein immunostaining, including pleomorphic Lewy bodies, synuclein-positive glial inclusions and widespread, severe neuritic dystrophy. We also discuss the relationship of this familial disorder to a Lewy body disease clinical spectrum, ranging from Parkinson’s disease to dementia with psychosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010051177
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  • 4
    Electronic Resource
    Electronic Resource
    Photosynthetic carbon reduction: high rates in the sea-surface microlayer (1989)
    Springer
    Marine biology 101 (1989), S. 411-417 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The ocean is a significant sink for increasing anthropogenic carbon dioxide emissions. The sea-surface microlayer (upper 50 μm layer) serves as the primary point for exchange of materials, including carbon dioxide, between the atmosphere and hydrosphere. We determined microalgal standing stocks and activities in microlayer and subsurface water from areas with (S) and without (NS) visible natural surface slicks in Sequim Bay, Washington, USA, in July 1984. Enrichment ratios (microlayer concentration: subsurface bulkwater concentration) were: phytoneuston population abundance, 37 (NS) to 154 (S); total chlorophylls, 1.3 (NS) to 18 (S); particulate carbon fixation, 2 (NS) to 52 (S); and dissolved carbon excretion, 17 (NS) to 63 (S). Photoinhibition of 36 to 89% occurred in phytoneuston under natural summer light-intensities. Slick samples had greater standing stocks and rates of primary production than non-slick samples. The species composition of phytoneuston was distinctly different from that of phytoplankton. These results suggest that phytoneuston form a unique community. Although carbon fixation in summer was less per individual in phytoneuston than in phytoplankton, because of their overall abundance at the air-sea interface, phytoneuston may play an important role in the transfer of CO2 from the atmosphere into ocean surface-water.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00428138
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  • 5
    Electronic Resource
    Electronic Resource
    The sea-surface microlayer: phytoneuston productivity and effects of atmospheric particulate matter (1984)
    Springer
    Marine biology 82 (1984), S. 293-300 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The sea-surface microlayer, the upper 50 μm of the ocean surface, provides a habitat for an important biota (the neuston), an interface for exchange of gases between the atmosphere and oceans and a site for deposition of anthropogenic metals and other materials from the atmosphere. Several recent studies have suggested that biochemical processes, including photosynthesis, in the microlayer are inhibited relative to the bulk seawater. We compared the biomass, species composition and productivity of phytoneuston to that of phytoplankton in Sequim Bay, Washington State, USA. Mean enrichment ratios (microlayer: bulk water concentrations) for bacteria, microalgae, chlorophyll pigments and photosynthesis (estimated gross) were 2 444, 380, 12 and 40, respectively. Compared to the bulk water, the microlayer had a unique assemblage of microalgae with a higher concentration of chlorophyll c. When exposed to high light intensities (summer) or metalrich urban atmospheric particulate matter, radiocarbonmeasured photosynthesis was lower in phytoneuston than in phytoplankton. Deposition of atmospheric particulate matter at rates similar to those occurring in urban coastal areas resulted in a significant (P〈0.01) reduction in radiocarbon-measured photosynthesis in the sea-surface microlayer. These apparent decreases in photosynthesis are believed to result from the extracellular release of 14C as glycolate or other soluble compounds and may not reflect a true decrease in gross primary productivity in the microlayer. Further measurements of the degree of extracellular carbon release will be necessary to quantify gross photosynthetic rates in the microlayer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00392409
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  • 6
    Electronic Resource
    Electronic Resource
    Sewage nutrient enrichment and phytoplankton ecology along the central coast of Lebanon (1976)
    Springer
    Marine biology 38 (1976), S. 315-325 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The abundance and taxonomic diversity of phytoplankton has been studied in relation to sewage pollution (proximity to outfalls) south of Beirut, Lebanon. Surface-water samples were collected from a series of beach stations extending from the American University of Beirut to 20 km south from June, 1973 to July, 1974. Samples were preserved, concentrated by settling, and the concentration of each taxon of phytoplankton enumerated in an inverted microscope. Water samples from the vicinity of two major sewer outfalls (Carlton and Khalde sewers) showed very high concentrations of NH4 +, NO2 -, NO3 - and PO4 -3, a greater total concentration of phytoplankton, and a lower taxonomic diversity than samples remote from outfalls. A considerable variation in the occurrence of species and dominance occurred along the pollution gradient. Blue-green algae and dinoflagellates were dominant in polluted waters, while diatoms dominated in cleaner water away from major sewage outflow. From the dominance and relative distribution of the taxa along the pollution gradient, certain taxa (Oscillatoria spp., Spirulina spp., Phormidium spp., Synochococcus custos and S. elongatus, Gymnodinium spp., and Prorocentrum spp.) emerge as indicator species of pollution. These changes correspond to a typical degradation of a complex community to a less mature state by the inflow of nutrient-rich sewage (eutrophication) along a coastal region about 10 km long.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00391371
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  • 7
    Electronic Resource
    Electronic Resource
    The Debye–Waller factors of the rubidium and cesium halides (1975)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 31 (1975), S. 249-252 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Computed mean-square displacements and Debye-Waller BK factors, derived using the deformation dipole model, are reported for the rubidium and cesium halides at 4.2, 80, and 300 °K. Experimental X-ray diffraction Debye-Waller factors, obtained at 300°K, are reported for CsCI, CsBr, and CsI. The calculated BK values are compared with these and other experimental values wherever such data exist. The differences between calculated and measured values at 4.2°K are not large but in three out of four cases lie outside the small experimental uncertainties quoted. At 300°K, on the other hand, the differences tend to be larger, but in about half of the cases are less than the experimental uncertainty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739475000502
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  • 8
    Electronic Resource
    Electronic Resource
    ApoE2 Allele, Down's Syndrome, and Dementia (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 777 (1996), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Notes: All individuals with Down's syndrome (trisomy 21-DS) develop the pathogenic hallmarks of Alzheimer's disease in old age (+40 years).1-4 The extent of pathology is variable, but it has been shown that the amount of β-amyloid pathology is variable and related to age and the degree of dementia.3 Thus, in DS, growing old is associated with a progressive pathological process which results in cognitive decline. However, neuropsychological studies of older DS subjects have identified a clinical dementia in only a proportion of cases.1-4These contradictory observations could be reconciled if some factor existed which modulated the rate and amount of β-amyloid pathology. Recent studies demonstrate an association between the apolipoprotein E4 (ApoE4) allele and the earlier age of onset in both sporadic8-9 and familial10 AD. Increased amounts of βamyloid pathology can also be related to the E4 allele. However, at present there are no data documenting the effects of ApoE genotype on the expression or degree of clinical symptoms of the disease. We have examined the ApoE genotype in a cohort of clinically evaluated elderly patients with DS in order to examine the effects of ApoE genotype on the clinical symptoms of dementia. We report here that, despite the presence of an active disease process, the ApoE E2 allele is associated with longevity and preservation of cognitive functioning.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1996.tb34428.x
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  • 9
    Electronic Resource
    Electronic Resource
    Flow Properties, Firmness and Stability of Double Cream Cheese Containing Whey Protein Concentrate (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 61 (1996), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: As estimated on-line, the viscosity after cooling of double cream cheese curd containing heat-denatured WPC (DCC +) increased from 1.4 Pa.s to 1.7 Pa.s when cooled to the range of 45°C to 24°C, and then decreased from 1.7 Pa.s to 1.0 Pa.s when cooled from 24°C to 15°C. The viscosity of DCC- (without heat-denatured WPC) increased from 1.5 Pa.s to 2.2 Pa.s at temperature shift from 40°C to 15.5°C. The firmness of stored DCC + and DCC-, respectively, decreased from 15.1N to 6.5N when cooled to temperatures from 45°C to 15°C, and from 17.9N to 9.9N when cooled from 40°C to 15.5°C, as recorded by cone penetrometry. The structure of DCC+ cooled to 15°C collapsed after penetrometry, and DCC+ cooled to 20°C destabilized during shearing in coaxial cylinder rheometer. A new phase in DCC+ based on milk fat globules liberated by cluster disruption may be the cause of the structural and textural instability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1996.tb12215.x
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  • 10
    Electronic Resource
    Electronic Resource
    1H and 23Na NMR Relaxation Studies of the NaCl/β-Lactoglobulin System Equilibrated at Various Water Activities (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 54 (1989), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: NMR relaxation times (T1) of 1H and 23Na were determined at 8, 14, 60, MHz and at 14, 52 MHz, respectively, in the NaCl/β-lactoglobulin system equilibrated at water activities ranging from 0.11 to 0.97. A two-state model was used for both nuclei which allowed the calculation of proportions of bound and free species. It was shown that bound water and Na+ increased at medium water activities in the presence of increasing NaCl. The discrepancy with adsorption isotherms data was explained by (1) limitations of the mass balance equation used to calculate interacting salt by gravimetry and (2) the fact that NMR probed the totality of ions in the vicinity of the protein, whereas adsorption isotherms were indicative of sodium choride tightly bound to the protein. It was also shown that the protein and Na+ shared available water molecules at medium and low water activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1989.tb07911.x
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