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  • Enterobacter agglomerans  (2)
  • Microbial pool  (2)
  • 5-fluorouracil  (1)
  • Antidromic potentials  (1)
  • Ash-free biomass  (1)
  • Autoradiography  (1)
  • Bone mineral analysis  (1)
Source
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Autoradiographic distribution of brainstem substance P binding sites in humans: Ontogenic study and relation to Sudden Infant Death Syndrome (SIDS) (1997)
    Springer
    Journal of neural transmission 104 (1997), S. 1101-1105 
    Details
    ISSN: 1435-1463
    Keywords: Autoradiography ; substance P ; ontogenesis ; sudden infant death syndrome ; SIDS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The precise distribution of substance P (SP) binding sites in the human brainstem was investigated in normal cases (3 fetuses and 24 newborns) and in 9 cases of Sudden Infant Death Syndrome (SIDS) by in vitro quantitative autoradiography. We discussed the widely but uneven distribution of SP binding sites as regards to the role of SP in brainstem cardio-respiratory ontogenic control and its possible involvement in SIDS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01273322
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Nitrogen availability to grain sorghum from organic and inorganic sources on sandy and clayey soil surfaces in a greenhouse pot study (1996)
    Springer
    Biology and fertility of soils 21 (1996), S. 271-276 
    Details
    ISSN: 1432-0789
    Keywords: 15N transformations ; Crop residues ; Soil texture ; Soil aggregation ; Microbial pool ; Microbial biomass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract In a greenhouse pot study, we examined the availability of N to grain sorghum from organic and inorganic N sources. The treatments were15N-labeled clover residues, wheat residues, and fertilizer placed on a sandy clay loam and loamy sand soil surface for an 8-week period. Soil aggregates formed under each soil texture were measured after 8 weeks for each treatment. Significantly greater 15N was taken up and recovered by grain sorghum in sandy clay loam pots compared with loamy sand pots. Greater 15N recovery was consistently observed with the inorganic source than the organic sources regardless of soil texture or time. Microbial biomass C and N were significantly greater for sandy clay loam soil compared with the loamy sand. Microbial biomass 15N was also significantly greater in the sandy clay loam treatment compared to the loamy sand. The fertilizer treatment initially had the greatest pool of microbial biomass 15N but decreased with time. The crop residue treatments generally had less microbial biomass 15N with time. The crop residues and soil texture had a significant effect on the water-stable aggregates formed after 8 weeks of treatments. Significantly greater water-stable aggregates were formed in the sandy clay loam than the loamy sand. Approximately 20% greater water-stable aggregates were formed under the crop residue treatments compared to the fertilizer only treatment. Soil texture seemed to be one of the most important factors affecting the availability of N from organic or inorganic N sources in these soils.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00334903
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Solubilization of hydroxyapatite by Enterobacter agglomerans and cloned Escherichia coli in culture medium (1997)
    Springer
    Biology and fertility of soils 24 (1997), S. 347-352 
    Details
    ISSN: 1432-0789
    Keywords: Key words Phosphate-solubilizing bacteria ; Hydroxyapatite ; Enterobacter agglomerans ; Organic acids ; Phosphate-solubilizing genes ; Rhizosphere ; Wheat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Phosphate-solubilizing bacteria (PSB) possessing the ability to solubilize insoluble inorganic phosphate were isolated from the rhizosphere soil of wheat. A laboratory study was conducted to investigate the solubilization of phosphate by a known PSB, Enterobacter agglomerans, and by a genetically manipulated bacterium, Escherichia coli. A second laboratory study investigated the release of P from E. agglomerans compared with known acids. For the first laboratory study, a cosmid (pHC79) library of phosphate-solubilizing gene(s) from E. agglomerans chromosome DNA was constructed in E. coli JM109. The clone JM109 (pKKY) showing phosphate solubilization properties was screened on standard medium containing hydroxyapatite (HY). The P concentration significantly increased at 5 and 10 days for JM109 (pKKY) compared with JM109 (pHC79), the control. Although the P concentration increased, there was no significant change in their pHs. Furthermore, an increase in colony-forming units (CFUs) was seen at 5 and 10 days for JM109 (pKKY) but not for JM109 (pHC79). Artificial acidification of the culture medium with HCl, citric acid, oxalic acid, and lactic acid was achieved by shaking for 48h. Acidification with these selected acids solubilized more HY than E. agglomerans growing for 42h at similar pHs. However, a high P concentration was measured in culture medium with E. agglomerans growing for 84h despite similar pHs. Our results suggest that acid production may play an important role in HY solubilization, but is not the sole reason for the increase in P concentration in culture medium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003740050256
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of phosphate-solubilizing bacteria and vesicular-arbuscular mycorrhizae on tomato growth and soil microbial activity (1997)
    Springer
    Biology and fertility of soils 26 (1997), S. 79-87 
    Details
    ISSN: 1432-0789
    Keywords: Key words Organic acids ; Phosphate-solubilizing ; bacteria ; Vesicular-arbuscular mycorrhizae ; Glomus etunicatum ; Enterobacter agglomerans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The interaction of vesicular-arbuscular mycorrhizae (VAM) and phosphate-solubilizing bacteria (PSB) on plant growth, soil microbial activities, and the production of organic acids was studied in non-sterile soil containing hydroxyapatite and glucose. Glomus etunicatum (VAM), a fungus, and Enterobacter agglomerans, a bacterium able to solubilize insoluble phosphate, were used as inocula. Three treatments and a control were used: inoculation with E. agglomerans (treatment E), inoculation with G. etunicatum (treatment G), inoculation with E. agglomerans+G. etunicatum (treatment E+G) and the control (C). Inoculation with E, G, or E+G had increased plant growth by days 35, 55, and 75 compared with the control. Microbial biomass carbon (C) and alkaline phosphatase activity in the rhizosphere generally increased with time. Alkaline phosphatase activity was higher in treatments G and E+G compared with the control at 35 and 55 days. The highest acid phosphatase activity was observed in treatment E at 35 days; however, this markedly decreased with time. A significantly higher soluble phosphorus (P) concentration was observed in treatments E and E+G on day 55 compared with C. However, there was no significant difference in soluble P concentration in the rhizosphere between treatments with time. The P concentration was greatest in all treatments on day 55. The highest oxalic acid concentration was observed in the rhizosphere of the non-sterile soil in E+G on day 35. Total N and P uptake in plants from treatments E and G were higher compared with the control. However, the highest N and P uptake was observed in treatment E+G. This study suggests a synergistic interaction between E. agglomerans and G. etunicatum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003740050347
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  • 5
    Electronic Resource
    Electronic Resource
    Earthworm response to rotation and tillage in a Missouri claypan soil (1999)
    Springer
    Biology and fertility of soils 29 (1999), S. 343-347 
    Details
    ISSN: 1432-0789
    Keywords: Key words Aporrectodea trapezoides ; Diplocardia singularis ; Population density ; Ash-free biomass ; Crop rotation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract  Agricultural management practices affect earthworm populations. A field experiment was conducted to determine the effect of two rotations and two tillage systems on earthworm population density and biomass in a claypan soil. The rotations were soybean/corn and wheat/corn, and the tillage systems were conventional tillage (chisel plowed and disked) and no-tillage. Earthworm and soil samples were collected in fall 1995, spring 1996, and fall 1996. Aporrectodea trapezoides and Diplocardia singularis were the species identified at the site. A. trapezoides accounted for 92–96% of the total earthworm population density and D. singularis accounted for only 4–8%. In a no-till system, soybean/corn rotation resulted in significantly greater population density of A. trapezoides compared with the wheat/corn rotation. Crop residue quality (low C:N ratio) and quantity were important factors in increasing A. trapezoides population density and biomass. Conventional tillage markedly decreased population density and biomass of both earthworm species. Our results suggest that rotation and tillage significantly affect earthworm population density and biomass.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003740050563
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  • 6
    Electronic Resource
    Electronic Resource
    Sex differences in geometry of the femoral neck with aging: A structural analysis of bone mineral data (1992)
    Springer
    Calcified tissue international 50 (1992), S. 24-29 
    Details
    ISSN: 1432-0827
    Keywords: Bone mineral analysis ; Hip strength analysis ; Age ; Femoral neck stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The greater hip fracture rate among elderly women is generally ascribed to differences in femoral neck strength between the sexes. Strength of a given bone is a function of both its material properties and the magnitudes of mechanical stresses within it. This study examined the hypothesis that these apparent strength differences between the sexes are due to dissimilarities in the restructuring of the femoral neck with age, which result in higher stresses in elderly women. Using Hip Strength Analysis, a computer program developed by the authors, femoral neck cross-sectional geometric properties for stress analyses were derived from bone mineral image data of 409 community living, white subjects ranging from 19 to 93 years of age. Though both sexes show declines in femoral neck bone mineral density (BMD) and cross-sectional area with age, only females show a decline in the cross-sectional moment of inertia (CSMI, a geometric index of bone rigidity). The lack of decline in male CSMI appears to be a result of a small but significant increase in femoral neck girth. Similar age-related changes have been observed in the femoral shaft by others. The net effect of these observed changes is that mechanical stresses in the femoral neck of females appear to increase at three times the rate per decade of those of males. These results lend support to the hypothesis that the higher fracture rate in elderly women is due, at least in part, to elevated levels of mechanical stress, resulting from a combination of greater bone loss and less compensatory geometric restructuring with age.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00297293
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  • 7
    Electronic Resource
    Electronic Resource
    Studies on the termination of sinus nerve afferents (1977)
    Springer
    Pflügers Archiv 369 (1977), S. 65-73 
    Details
    ISSN: 1432-2013
    Keywords: Carotid sinus nerve ; Primary afferent fibres ; Nucleus of the tractus solitarius ; C-fibres ; Antidromic potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Compound action potentials evoked by electrical stimulation in the brainstem of anaesthetized, paralyzed cats and rabbits were recorded distally in the carotid sinus nerve. The latencies of the components of the responses were indicative of fibres with conduction velocities between 0.5 and 32 m/s. These include both myelinated and unmyelinated fibres. Using histological reconstructions of the ‘responsive sites’, the termination of the primary afferent fibres of the sinus nerve within the medulla was mapped. In both cat and rabbit these responsive sites were restricted to thedorsomedial medulla in the vicinity of the NTS 0–3 mm rostral to the obex. Although in the cat the fast conducting myelinated fibres (conduction velocities 〉12.5 m/s) were discretely localized to the ventrolateral area of the NTS, the slower conducting myelinated and unmyelinated fibres were found more diffusely, spreading into areas dorsal and medial to the NTS. In the rabbit the terminals of all types of fibre were mainly confined to the NTS although some C fibres appeared to be grouped in the juxta-alar region. Responses were never evoked from the medial reticular formation or nucleus ambiguus in either cats or rabbits. The organization of the sinus nerve input to the medulla is discussed in the light of these results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00580812
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  • 8
    Electronic Resource
    Electronic Resource
    Nitrogen availability to grain sorghum from organic and inorganic sources on sandy and clayey soil surfaces in a greenhouse pot study (1996)
    Springer
    Biology and fertility of soils 21 (1996), S. 271-276 
    Details
    ISSN: 1432-0789
    Keywords: Key words15N transformations ; Crop residues ; Soil texture ; Soil aggregation ; Microbial pool ; Microbial biomass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract In a greenhouse pot study, we examined the availability of N to grain sorghum from organic and inorganic N sources. The treatments were 15N-labeled clover residues, wheat residues, and fertilizer placed on a sandy clay loam and loamy sand soil surface for an 8-week period. Soil aggregates formed under each soil texture were measured after 8 weeks for each treatment. Significantly greater 15N was taken up and recovered by grain sorghum in sandy clay loam pots compared with loamy sand pots. Greater 15N recovery was consistently observed with the inorganic source than the organic sources regardless of soil texture or time. Microbial biomass C and N were significantly greater for sandy clay loam soil compared with the loamy sand. Microbial biomass 15N was also significantly greater in the sandy clay loam treatment compared to the loamy sand. The fertilizer treatment initially had the greatest pool of microbial biomass 15N but decreased with time. The crop residue treatments generally had less microbial biomass 15N with time. The crop residues and soil texture had a significant effect on the water-stable aggregates formed after 8 weeks of treatments. Significantly greater water-stable aggregates were formed in the sandy clay loam than the loamy sand. Approximately 20% greater water-stable aggregates were formed under the crop residue treatments compared to the fertilizer only treatment. Soil texture seemed to be one of the most important factors affecting the availability of N from organic or inorganic N sources in these soils.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00334903
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    A phase I study of gemcitabine, 5-fluorouracil and leucovorin in patients with advanced, recurrent, and/or metastatic solid tumors (1998)
    Springer
    Investigational new drugs 16 (1998), S. 325-330 
    Details
    ISSN: 1573-0646
    Keywords: gemcitabine ; 5-fluorouracil ; leucovorin ; phase I study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Introduction: This was a dose escalation phase I trial designed to establish the MTD (maximum tolerated dose) and toxicity profile of the combination of gemcitabine, leucovorin and 5-fluorouracil (5-FU). Methods: Standard eligibility criteria were required for patients with advanced malignancy to enrol. Gemcitabine was escalated from an initial dose of 800 mg/m2. Gemcitabine was administered prior to leucovorin (25 mg/m2) followed by bolus 5-FU (600 mg/m2) every week for 3 weeks followed by 1 week of rest. Results: Of 21 patients enrolled, 20 were eligible for MTD determination. Patients received a median of three 4-week cycles of chemotherapy (range: 1 to 8 cycles). Toxicity was predominantly hematologic or gastroenterologic. Four dose levels were studied. At a gemcitabine dose of 1,500 mg/m2 systemic symptoms of fatigue accompanied hematologic toxicity and patients refused further therapy. At 1,250 mg/m2, full dose intensity was not delivered during the first cycle in 7 of 8 patients treated. Therefore, 1,000 mg/m2 was established as the recommended phase II dose for gemcitabine in this study. Antitumor activity was seen at all dose levels. Conclusions: The combination of gemcitabine, leucovorin and 5-FU was tolerable at full doses of all 3 drugs with an expected toxicity profile. Recommended phase II dose for gemcitabine was 1,000 mg/m2. Initial evidence of clinical activity was seen in a variety of tumor types.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006242005837
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