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  • 1
    ISSN: 1432-2072
    Keywords: 8-OH-DPAT ; Feeding ; Drinking ; Palatability ; Appetite ; Fenfluramine ; Satiety ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The 5-HT1A agonist 8-OH-DPAT, at a dose of 30 μg/kg, enhanced the consumption of sweetened wet mash and sweetened milk in non-deprived rats. In partially satiated rats, sensitivity to the hyperphagic effect of 8-OH-DPAT on wet mash intake was substantially increased, so that the minimally effective dose was reduced to 3 μg/kg. Similarly, 8-OH-DPAT was more efficacious in increasing milk intake in satiated rats. Thus, 30 and 40 μg/kg 8-OH-DPAT produced a 4-fold increase of milk intake in completely satiated rats compared to a 2-fold increase in partially satiated animals at a dose of 30 μg/kg. The increased intake of liquid and wet mash diets observed after treatment with low doses of 8-OH-DPAT argues against the involvement of non-specific gnawing in the increased consumption of solid food produced by the drug. Rather, the data suggest that 8-OH-DPAT may specifically stimulate appetite by counteracting a tonic serotonergic inhibition of feeding. The present experiments also showed that 8-OH-DPAT attenuates fenfluramine-induced anorexia which is thought to depend on increased serotonergic neurotransmission.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Agriculture and human values 14 (1997), S. 337-352 
    ISSN: 1572-8366
    Keywords: National parks ; Conservation ; Preservation ; France ; United Kingdom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Greenline parks are typically regions of mixed agricultural,grazing, and forest lands of sufficient scenic and/orecological value to merit conservation and preservationunder a land-use management plan for land largely in privateownership. The Parcs Naturels Régionaux (PNR) are anational system of greenline parks created in France in1967 to protect agriculture and other values in less favoredareas (typically hills or low mountains) suffering depopulationand economic deprivation aggravated by the Common AgriculturalPolicy created under the European Economic Community in 1956with a major objective of self-sufficiency in food production.Two developments contributing to creation of the PNR were themechanization of French agriculture and increasing environmentalawareness in France. The PNR emphasizes rural agriculturaldevelopment, conservation, and recreation, but ecologicalpreservation has increased in importance, as reflected inrecent policy changes. The national parks of the United Kingdomare a system of greenline parks slightly older than the PNR.Recent research has allowed comparative studies of the twosystems, leading to the conclusion that the British NationalParks have suffered from heavy-handed centralized planningthat has alienated local farmers and communities, while thePNR, under more local control, has neglected some of itsconservation and preservation responsibilities. However,recent policy reform promises to improve the PNR throughmore rigorous enforcement of conservation and ecologicalgoals by the central government.
    Type of Medium: Electronic Resource
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