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  • 1
    Electronic Resource
    Electronic Resource
    The effects of clofibrate on acetyl-CoA carboxylase activity in hepatocytes (1971)
    Springer
    Cell & tissue research 119 (1971), S. 321-325 
    Details
    ISSN: 1432-0878
    Keywords: Hepatocytes ; A CoA Carboxylase ; Clofibrate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cytochemical localization techniques and electron microscopy were used to evaluate the effects of clofibrate on acetyl-CoA carboxylase activity. It was demonstrated that the drug inhibited the activity of acetyl-CoA carboxylase in rat hepatocytes. Although the results in one of these experiments were somewhat variable, it is suggested that the inhibition of acetyl-CoA carboxylase may be the mechanism by which clofibrate exerts its hypolipidemic effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431290
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