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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 85 (1987), S. 128-137 
    ISSN: 0942-0940
    Keywords: ACNU ; BCNU ; intracarotid infusion ; malignant glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thirty patients with malignant gliomas were treated by operation, radiotherapy and additional intracarotid infusions of ACNU and BCNU. Positive results were obtained in the treatement of oligodendrogliomas and astrocytomas grade III and IV. On the contrary, the results in cases of glioblastoma multiforme were disappointing: neither survival time nor quality of life had been significantly improved. The protective effect of phenobarbitone against systemic toxicity by ACNU was not always confirmed in this study. Based on literature reports and our own experience the indications, technical aspects, unexpected complications and results of this therapeutic approach are discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 337 (1974), S. 191-194 
    ISSN: 1435-2451
    Keywords: Brain Injuries ; Brain Edema ; Autoregulation of the Cerebral Circulation ; Raised Intracranial Pressure ; Cerebrale Durchblutungsautoregulation ; Intrakranielle Drucksteigerung ; Traumatische Hirnschädigung ; Hirnödem
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Hirnverletzte ist wegen der Gefahr traumatischer intrakranieller Hämatome und wegen des Ausfalles der schützenden Durchblutungsautoregulation des Gehirns besonders gefährdet. Blutdruckabfall, Anämie, verminderterpO2 des Blutes und Temperaturanstieg, die vom Hirngesunden ohne Schaden toleriert werden, können die Verletzungsfolgen entscheidend verschlimmern. Die therapeutischen Konsequenzen werden besprochen.
    Notes: Summary The patient with head injuries is particularly at risk, due to the possibility of intracranial hematomas and the failure of the autoregulation of the cerebral circulation. A fall in blood pressure and oxygenation, anemia, and/or increased body temperature, which are tolerated with no harm by patients who have not suffered brain damage, can make the results of injury significantly worse. The therapeutic consequences are discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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