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  • 1
    Electronic Resource
    Electronic Resource
    Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas (1987)
    Springer
    Acta neurochirurgica 85 (1987), S. 128-137 
    Details
    ISSN: 0942-0940
    Keywords: ACNU ; BCNU ; intracarotid infusion ; malignant glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thirty patients with malignant gliomas were treated by operation, radiotherapy and additional intracarotid infusions of ACNU and BCNU. Positive results were obtained in the treatement of oligodendrogliomas and astrocytomas grade III and IV. On the contrary, the results in cases of glioblastoma multiforme were disappointing: neither survival time nor quality of life had been significantly improved. The protective effect of phenobarbitone against systemic toxicity by ACNU was not always confirmed in this study. Based on literature reports and our own experience the indications, technical aspects, unexpected complications and results of this therapeutic approach are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01456109
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Spinal elastance measurement in patients with spondylogenic narrowing of the spinal canal (1980)
    Springer
    Acta neurochirurgica 52 (1980), S. 281-288 
    Details
    ISSN: 0942-0940
    Keywords: Spinal elastance ; narrow cervical spinal canal ; spondylogenic myelopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Spinal elastance and the time course of pressure decrease after saline injection into the lumbar subarachnoid space was measured in a control group and in a group of patients with spondylogenic narrowing of the cervical spinal canal. The elastance is higher with retroflexion of the head than with anteflexion. This is more pronounced in degenerative diseases of the spine, proving the existence of a pincers mechanism. High elastance values at high volume changes indicate a narrowing of the cervical spinal canal. With a normal spinal canal the pressure decrease shows a slow monoexponential slope (T/2=100.8±13.4 seconds). In patients with partial obstruction of the spinal canal, especially with retroflexion of the head, a secondary pressure increase after termination of the volume injection was observed. This secondary pressure increase decreases in a biexponential manner with a fast slope (T/2=37.62±15.88 seconds) followed by a slow slope. With severe obstructions a plateau remained. This easily performed and well-tolerated measurement can be of aid in the quantification of obstructions of the spinal subarachnoid space.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01402083
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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