Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Intracellular bicarbonate in single cells of Necturus kidney proximal tubule (1974)
    Springer
    Pflügers Archiv 349 (1974), S. 295-299 
    Details
    ISSN: 1432-2013
    Keywords: Bicarbonate Microelectrode ; Intracellular Bicarbonate ; Cell Bicarbonate ; Kidney Cell Bicarbonate ; Kidney Cell pH ; Proximal Tubule Cell Bicarbonate ; Necturus Maculosus Proximal Tubule
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The intracellular bicarbonate concentration in the cytoplasmic water of kidney cells of Necturus was determined by means of double-barreled HCO3 −-selective liquid ion-exchange microelectrodes. These microelectrodes permit the simultaneous determination of intracellular HCO3 − and membrane PD of single cells. The fact that these double-barreled microelectrodes yielded a normal peritubular cell membrane electrical PD (70 m V) may be taken as evidence against any significant cellular damage by the electrodes. This electrometric study yielded a mean intracellular [HCO3 −] in single proximal tubule cells of Necturus of 11.1±0.6 mM, a value which is more than an order of magnitude higher than that predicted for a Donnan-type electrochemical equilibrium distribution of HCO3 − ions. Thus there is a net electrochemical gradient favoring the passive efflux of HCO3 − ions across both individual cell membranes. The movement of HCO3 − ions from cell-to-interstitium would contribute to the renal acidification function. Across the luminal cell membrane the two possible mechanisms are either active reabsorption (lumen-to-cell) of HCO3 − ions as such or active H+ secretion (cell-to-lumen). Our directly measured relatively high intracellular [HCO3 −] and the associated calculated relatively alkaline kidney cell pH of 7.44 are both more consistent with the H+ secretion hypothesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588415
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    A second-order ADI scheme for three-dimensional parabolic differential equations (1998)
    New York, NY [u.a.] : Wiley-Blackwell
    Numerical Methods for Partial Differential Equations 14 (1998), S. 159-168 
    Details
    ISSN: 0749-159X
    Keywords: ADI scheme ; parabolic differential equation ; stability ; Mathematics and Statistics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: A second-order unconditionally stable ADI scheme has been developed for solving three-dimensional parabolic equations. This scheme reduces three-dimensional problems to a succession of one-dimensional problems. Further, the scheme is suitable for simulating fast transient phenomena. Numerical examples show that the scheme gives an accurate solution for the parabolic equation and converges rapidly to the steady state solution. © 1998 John Wiley & Sons, Inc. Numer Methods Partial Differential Eq 14:159-168, 1998
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...