ISSN:
0138-4988
Keywords:
Life Sciences
;
Life Sciences (general)
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Most mathematical models for describing the physiological state in fermentations lead to solutions of the so-called “stiff differential systems” during simulation on a digital computerThere is no suitable conventional software for solving these systemsAs a result of a relatively extensive screening of suitable methods for the solution of “stiff” differential systems (about 200 methods) it may be concluded that the semiimplicit RUNGE-KUTTA-formulas of the ROSENBROCK type, which constitute a part of the collection of programmes STIFFSOLVER-80, are optimal for the simulation of fermentation processesFor determining kinetic parameters from integral data the authors use the system of programmes BIOKINTheir practical application is discussed for 3 examples: 1Growth of the yeast Saccharomyces cerevisiae and changes in the content of specific compounds (proteins and ergosterol)2Quantitative evaluation of “;direct oxygen transfer” in the submerged culture.3Biosynthesis of a new antibiotic substance mucidin.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/abio.370020202
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