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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical chemistry accounts 50 (1978), S. 67-73 
    ISSN: 1432-2234
    Keywords: Amino groups of nucleic acid bases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Quantum chemical calculations are reported on the deprotonation and protonation of the amino groups of the nucleic acid bases adenine, guanine and cytosine, in an attempt to compare the relative reactivities of these groups. In the light of renewed interest in the amino groups as reactive sites for certain carcinogenic and carcinostatic agents, we discuss the possible significance of our results for the interpretation of these molecular interactions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical chemistry accounts 53 (1979), S. 175-181 
    ISSN: 1432-2234
    Keywords: B-DNA helix ; Acetylaminofluorene, carcinogenic, binding of ∼ to DNA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The influence of a single and double helical DNA environment on the molecular electrostatic potentials at the C8 and amino sites of guanine and adenine are studied. The results are employed in a tentative explanation of the variation in binding sites of N-acetoxy-N-2-acetylaminofluorene with DNA, following whether the nucleic acid is in a native or denatured state.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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