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  • Ascending Pathways  (2)
  • Acid inhibitory drugs  (1)
  • Behandlung  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 337 (1972), S. 135-146 
    ISSN: 1432-2013
    Keywords: Deiters Neurones ; EPSPs ; Mossy Fibre Collaterals ; Ascending Pathways
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out on cats, the chloralose anesthesia having been maintained by small doses of Thiopental in about half of the experiments. Intracellular recordings were evaluated from 256 Deiters neurones, which received EPSPs and/or IPSPs upon stimulation of the spinal cord. In respect to excitation, in 70% of these cells, stimulation of the spinal cord at C2-level evoked short latency EPSPs, which showed a bimodal latency distribution. Together with EPSP-latencies observed on stimulation of the lumbar cord the results indicate that a small group of EPSPs is evoked monosynaptically, whilst a major group is mediated via disynaptic linkages of fast conducting fibres. The possibility of a trisynaptic linkage is discussed. Deiters neurones can show rhythmic stimuluslocked discharges, probably based on the organization of synaptic excitation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 337 (1972), S. 119-134 
    ISSN: 1432-2013
    Keywords: Deiters Neurones ; Excitation ; Inhibition ; Cerebellum ; Ascending Pathways
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out on cats anesthetized with chloralose, small doses of Thiopental being added in about half of the animals. Recordings were made from neurones located in Deiters' nucleus. Single shocks applied to the spinal cord evoked membrane potential changes consisting of different types of PSPs. Current analysis revealed: EPSPs, IPSPs, and potential changes due to disinhibition; such components differing in their latencies. Upon stimulation at C2, there were EPSPs with brief (mean 1.7 ms) and longer (mean 5.8 ms) latencies, denoted “EE” and “CE”, respectively. Also, IPSPs showed up with brief (mean 3.6 ms, “MI”) and longer (mean 7.3 ms, “CI”) latencies. Moreover, there was a prolonged inhibition usually turning into a longlasting (up to several hundred milliseconds) disinhibitory depolarization. Of Deiters neurones exhibiting PSPs upon spinal cord stimulation, 66% showed the complete synaptic pattern, 34% short latency or long latency components in isolation. The patterns obtained intracellularly corresponded well to discharge patterns recorded extracellularly. The results were essentially similar in control experiments performed on precollicularly decerebrated cats.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 652-652 
    ISSN: 1435-2451
    Keywords: Patients with organ failure ; Acid secretion ; Gastrin ; Acid inhibitory drugs ; Patienten mit Organinsuffizienz ; Säuresekretion ; Gastrin ; Säurehemmende Medikamente
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 9 Patienten auf der Intensivstation unserer Klinik mit einer oder mehrfacher Organinsuffizienz betrug die mittlere Säuresekretion/h unter Placebo 31 mEq, Cimetidin (8 × 200 mg i.v.) 7,5 mEq, Pirenzepin (4 × 10 mg i.v.) 22 mEq und Cimetidin + Pirenzepin 4,0 mEq. Alle Patienten zeigten eine Hypergastrinämie, die unter Placebo als auch unter der Medikamenten-Gabe bestehen blieb. Die erhöhten Gastrinwerte könnten einen Stimulus für die hohe Säuresekretion in diesen Streßulcus gefährdeten Patienten darstellen.
    Notes: Summary In nine patients at our intensive care unit with one or multiple organ failure, mean acid secretion/h was measured with placebo 31 mEq, cimetidine (8 × 200 mg IV) 7.5 mEq, pirenzepine (4 × 10 mg IV) 22 mEq and cimetidine + pirenzepine 4.0 mEq. All patients showed hypergastrinemia that was present under placebo as well as drug regimen. Increased gastrin might be one stimulus for increased acid secretion in these high-risk patients for stress ulceration.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1435-2451
    Keywords: Multiple endocrine adenomatosis ; Endocrine surgery ; Diagnostic procedures ; Treatment ; Multiple endokrine Adenomatosen ; Endokrine Chirurgie ; Diagnostik ; Behandlung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Vom 1.1.1960 bis 15.4.1980 wurden 3746 Patienten wegen endokriner Erkrankungen (Hyperparathyreoidismusn = 301, Pankreasn = 60, Phäochromocytomn = 34, Nebennierenrinden = 109, Struman = 3242) operiert. Hierunter fanden sich ab 1969 7 Patienten mit MEA I und 3 Patienten mit MEA II. Charakteristica, Diagnostik, Operationsindikation und Therapie der MEA-Syndrome sowie die eigenen Ergebnisse werden dargestellt.
    Notes: Summary From January 1, 1960 — April 15, 1980, 3746 patients were operated on for endocrine diseases (hyperparathyroidismn = 301, pancreasn = 60, pheochromocytoman = 34, adrenal cortexn = 109, goitern = 3242). Among these, 7 patients had the MEA I syndrome and 3 the MEA II syndrome since 1969. Characteristics, diagnostic procedures, indication for operation and treatment of MEA syndromes as well as own results are described.
    Type of Medium: Electronic Resource
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