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  • Deiters Neurones  (3)
  • Acid secretion  (1)
  • Deiters neurones  (1)
  • Deiters' nucleus  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Neuronal activity in the lateral vestibular nucleus of the cat (1975)
    Springer
    Pflügers Archiv 360 (1975), S. 301-320 
    Details
    ISSN: 1432-2013
    Keywords: Cerebellar afferents ; Deiters neurones ; Postsynaptic potentials ; Purkinje cell inhibition ; Somatic afferents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The synaptic input to Deiters neurones evoked by stimulation of peripheral somatic nerves was measured by intracellular recordings. EPSPs with broad receptive fields and latencies which indicate polysynaptic connexions were commonly evoked from the FRA. In other cells, low threshold cutaneous afferents were effective at rather short latencies suggesting oligosynaptic connexions from fast ascending fibres. One example was found of EPSPs due to low threshold muscle afferents. IPSPs due to climbing fibre activation of Purkinje cells as observed in most of the neurones were evoked by cutaneous volleys above 1.5–2.0 T and muscle volleys above 5T (above 3–3.5T in case of Q). Often, IPSPs were evoked by stimulation of nerves, to the segmental level of which the vestibulospinal neurone under investigation projected. A small proportion of cells received short latency IPSPs involving direct fast mossy fibre tracts, which were evoked from low threshold cutaneous afferents. IPSPs due to polysynaptic mossy fibre activation of Purkinje cells were evoked from the FRA bilaterally and from ipsilateral cutaneous afferents at 1.5–2.0T (“prolonged inhibition”). Prolonged excitatory/inhibitory events mediated by mossy fibre pathways may be involved in quadruped locomotion or tother processes making use of a broad motor integration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00579322
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Neuronal activity in the lateral vestibular nucleus of the cat (1972)
    Springer
    Pflügers Archiv 337 (1972), S. 147-162 
    Details
    ISSN: 1432-2013
    Keywords: Deiters Neurones ; Mossy Fibre Afferents ; Climbing Fibre Afferents ; Purkinje Cell Inhibition ; Harmaline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intracellular records from 203 neurones located in Deiter's nucleus were evaluated in respect to IPSPs evoked by stimulation of the spinal cord. In 85% of the cells, short latency IPSPs were observed (less than 4.5 ms from C2-level), attributable to fast conducting pathways. The majority of them (3–4.5 ms) includes activity transmitted via the cerebellar cortex, while latencies between 1.0 and 2.9 ms as observed for roughly 10% of the early IPSPs, are too short to include cerebellum. IPSPs with longer latencies (mean 7.3 ms from C2-level) were found in 75% of the cells. Low conduction velocity of their spinal pathways and other criteria suggest that spino-olivo-climbing fibre systems including the cerebellar cortex are involved. The latter type of IPSP often shows a complex configuration, expainable by reflex discharges of olivary neurones and disinhibitory phenomena coupled to climbing fibre activation. Clean, rhythmic IPSPs were seen after injection of harmaline.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587837
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Neuronal activity in the lateral vestibular nucleus of the cat (1972)
    Springer
    Pflügers Archiv 337 (1972), S. 135-146 
    Details
    ISSN: 1432-2013
    Keywords: Deiters Neurones ; EPSPs ; Mossy Fibre Collaterals ; Ascending Pathways
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out on cats, the chloralose anesthesia having been maintained by small doses of Thiopental in about half of the experiments. Intracellular recordings were evaluated from 256 Deiters neurones, which received EPSPs and/or IPSPs upon stimulation of the spinal cord. In respect to excitation, in 70% of these cells, stimulation of the spinal cord at C2-level evoked short latency EPSPs, which showed a bimodal latency distribution. Together with EPSP-latencies observed on stimulation of the lumbar cord the results indicate that a small group of EPSPs is evoked monosynaptically, whilst a major group is mediated via disynaptic linkages of fast conducting fibres. The possibility of a trisynaptic linkage is discussed. Deiters neurones can show rhythmic stimuluslocked discharges, probably based on the organization of synaptic excitation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587836
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Neuronal activity in the lateral vestibular nucleus of the cat (1972)
    Springer
    Pflügers Archiv 337 (1972), S. 119-134 
    Details
    ISSN: 1432-2013
    Keywords: Deiters Neurones ; Excitation ; Inhibition ; Cerebellum ; Ascending Pathways
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out on cats anesthetized with chloralose, small doses of Thiopental being added in about half of the animals. Recordings were made from neurones located in Deiters' nucleus. Single shocks applied to the spinal cord evoked membrane potential changes consisting of different types of PSPs. Current analysis revealed: EPSPs, IPSPs, and potential changes due to disinhibition; such components differing in their latencies. Upon stimulation at C2, there were EPSPs with brief (mean 1.7 ms) and longer (mean 5.8 ms) latencies, denoted “EE” and “CE”, respectively. Also, IPSPs showed up with brief (mean 3.6 ms, “MI”) and longer (mean 7.3 ms, “CI”) latencies. Moreover, there was a prolonged inhibition usually turning into a longlasting (up to several hundred milliseconds) disinhibitory depolarization. Of Deiters neurones exhibiting PSPs upon spinal cord stimulation, 66% showed the complete synaptic pattern, 34% short latency or long latency components in isolation. The patterns obtained intracellularly corresponded well to discharge patterns recorded extracellularly. The results were essentially similar in control experiments performed on precollicularly decerebrated cats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587835
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Neuronal activity in the lateral vestibular nucleus of the cat (1975)
    Springer
    Pflügers Archiv 360 (1975), S. 321-336 
    Details
    ISSN: 1432-2013
    Keywords: Deiters' nucleus ; Flexor reflex afferents ; Purkinje cell inhibition ; Positive field potentials ; Spino-olivocerebellar paths
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The spatial distribution of inhibitory effects mediated by spino-olivocerebellar pathways and evoked by stimulation of the FRA was studied in Deiters' nucleus by intracellular recordings and extracellular measurements of positive field potentials. At a given recording site individual nerves greatly varied in their effectiveness: Q and Saph, Tib and FDL were usually the most effective, while GS had very little effect. When comparing several recording sites, various patterns of dominating and nondominating nerves were found, resulting in a somewhat patchy distribution of responses. The results were supported by intracellular recordings, which showed that CF-mediated IPSPs can be evoked from a limited number of nerves only. The findings show that a discriminative pattern exists in the FRA-evoked spino-olivocerebellar-mediated inhibition. In addition, Deiters neurones were found in which the inhibition was evoked from a large number of fore- and hindlimb nerves. Such a generalized inhibitory pattern may be involved in interlimb coordination during locomotion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00579323
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    312. Verhalten von Magensäure und Serum-Gastrin bei Streßulcus-gefährdeten Patienten (1981)
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 652-652 
    Details
    ISSN: 1435-2451
    Keywords: Patients with organ failure ; Acid secretion ; Gastrin ; Acid inhibitory drugs ; Patienten mit Organinsuffizienz ; Säuresekretion ; Gastrin ; Säurehemmende Medikamente
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 9 Patienten auf der Intensivstation unserer Klinik mit einer oder mehrfacher Organinsuffizienz betrug die mittlere Säuresekretion/h unter Placebo 31 mEq, Cimetidin (8 × 200 mg i.v.) 7,5 mEq, Pirenzepin (4 × 10 mg i.v.) 22 mEq und Cimetidin + Pirenzepin 4,0 mEq. Alle Patienten zeigten eine Hypergastrinämie, die unter Placebo als auch unter der Medikamenten-Gabe bestehen blieb. Die erhöhten Gastrinwerte könnten einen Stimulus für die hohe Säuresekretion in diesen Streßulcus gefährdeten Patienten darstellen.
    Notes: Summary In nine patients at our intensive care unit with one or multiple organ failure, mean acid secretion/h was measured with placebo 31 mEq, cimetidine (8 × 200 mg IV) 7.5 mEq, pirenzepine (4 × 10 mg IV) 22 mEq and cimetidine + pirenzepine 4.0 mEq. All patients showed hypergastrinemia that was present under placebo as well as drug regimen. Increased gastrin might be one stimulus for increased acid secretion in these high-risk patients for stress ulceration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01287146
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    Paper (German National Licenses)
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