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  • 1
    Electronic Resource
    Electronic Resource
    The effect of dilazep on blood flow and oxygen handling in the early stages of canine myocardial infarction (1974)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 281 (1974), S. 427-436 
    Details
    ISSN: 1432-1912
    Keywords: Dilazep ; Adenosine Potentiation ; Myocardial Blood Flow ; Myocardial Infarction ; Coronary Stealing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of dilazep, a drug which potentiates the actions of adenosine, were examined in a canine preparation that enabled simultaneous measurements to be made of blood flow both in ischaemic areas, and in essentially normal areas, of the canine myocardium. In doses which caused marked and sustained increases in blood flow to the normal myocardium, dilazep did not change either blood flow in the developing infarct or the trans-ventricular perfusion pressure (diastolic peripheral coronary pressure minus left ventricular end-diastolic pressure). Despite the lack of effect on infarct blood flow, the oxygen tension of the blood draining the infarcting area was markedly elevated. It is concluded that dilazep may open up blood vessels in an acutely ischaemic area which do not take part in tissue exchange, and may therefore decrease the efficiency of the myocardial circulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00499437
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Minimum norm quadratic estimation of components of spatial covariance (1985)
    Springer
    Mathematical geology 17 (1985), S. 517-525 
    Details
    ISSN: 1573-8868
    Keywords: Spatial covariance ; generalized covariance ; quadratic estimator ; unbiased estimator ; minimum norm ; nugget effect ; structural analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Notes: Abstract Quadratic estimators of components of a nested spatial covariance function are presented. Estimators are unbiased and possess a minimum norm property. Inversion of a covariance matrix is required but, by assuming that spatial correlation is absent, a priori, matrix inversion can be avoided. The loss of efficiency that results from this assumption is discussed. Methods can be generalized to include estimation of components of a generalized polynomial covariance assuming the underlying process to be an intrinsic random function. Particular attention is given to the special case where just two components of spatial covariance exist, one of which represents a nugget effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01032106
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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