ISSN:
1433-8580
Keywords:
Adrenal hyperplasia
;
Metapyralone
;
131I-6β-Iodocholesterol
;
Irradiation
;
Rats
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Marked weight reduction of rat adrenals was observed after131I-6β-Iodocholesterol administration whether or not the animals were treated with metapyralone. Damage or even histologic changes of the adrenals have not been found. Though the radiation dose is high with the applied dose of131I-6β-Iodocholesterol and might limit or even prevent its application in the treatment of human adrenal disease, the influence of endogenous irradiation on rat adrenals is obvious and justifies further investigations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01851404
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