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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 57 (1988), S. 456-461 
    ISSN: 1439-6327
    Keywords: Endurance training ; Erythrocytes ; 2,3-DPG ; Hexokinase ; Pyruvate kinase ; Glucose-6-phosphate dehydrogenase ; Glutathione reductase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The erythrocyte 2,3-diphosphoglycerate concentration (2,3-DPG) and the activity of red cell hexokinase, pyruvate kinase, glucose-6 phosphate dehydrogenase and gluthatione reductase were studied in 27 normal volunteers before and after 2 and 4 months of physical endurance training. The 4 months of training increased maximal oxygen uptake and physical working capacity (PWC130) by 16% (p〈0.001) and 29% (p〈0.001) respectively. Resting heart rate was decreased (p〈0.001) by 11 beats·min−1. With 2 months of training the erythrocyte 2,3-DPG concentration increased by 9% (p〈0.001); with 4 months training the increase was only 4% (p〈0.05). The training-induced increase in red cell 2,3-DPG was not accompanied by enhanced activity of erythrocyte hexokinase, pyruvate kinase, glucose-6 phosphate dehydrogenase or glutathione reductase. It is concluded that the rise in red cell 2,3-DPG induced by physical endurance training is not due to activation of red cell glycolytic enzymes or the enzymes involved in the pentose-phosphate cycle
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 59 (1989), S. 296-302 
    ISSN: 1439-6327
    Keywords: Marathon ; Intra-erythrocyte cations ; Sodium ; Potassium ; Aldosterone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The intracellular concentrations of sodium [Na+] and potassium [K+] and the water content in human erythrocytes were investigated in 21 male runners before and after a marathon. From 2 to 5 min after the race, the intra-erythrocyte [K+] was significantly decreased (p〈0.001) by 7% whereas the plasma [K+], intra-erythrocyte [Na+] and the erythrocyte water content were unchanged. The change in the intra-erythrocyte [K+] observed immediately after the marathon, was negatively correlated with the race time (r=−0.44;p〈0.05). Furthermore, the change in the plasma [K+] (r=−0.64;p〈0.001) and the amount of K+ excreted in the urine during the race (r=0.54;p〈0.05) were also, respectively, negatively and positively correlated with the race time. It is concluded that during prolonged physical exercise the erythrocytes could serve as a kind of K+ reservoir that is drained with increasing magnitude of body K+ loss. This might explain why in the faster marathon runners, in whom the urinary K+ loss is smaller and the K+ intake is greater than in the slower runners during race, the intra-erythrocyte [K+] is unchanged after a marathon whereas in the slower runners it is decreased.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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