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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 32 (1973), S. 87-98 
    ISSN: 1439-6327
    Keywords: Stress Relaxation ; Tendon ; Peroneus longus m. ; Peroneus brevis m. ; Influence of Age ; Relaxationseigenschaft ; Sehnen ; M. peroneus longus ; M. peroneus brevis ; Alterseinflu\
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Dehnt man eine Sehne bis zu einer bestimmten Spannung und hÄlt dann die LÄnge konstant, so fÄllt die Spannung zuerst schnell und dann zunehmend langsamer ab. Diese „ReIaxationseigenschaft“ wurde an 177 nichtkonservierten Sehnen des M. peroneus longus und M. peroneus brevis menschlicher Leichen (Alter 39 bis 93 Jahre) mit variierter Ausgangsspannung systematisch untersucht. Die Relaxationswerte nach 5 und nach 60 sec wurden statistisch ausgewertet. Die Relaxation ist beim 60 sec-Wert annÄhernd der Ausgangsspannung proportional, der relative 5 sec-Wert wird mit zunehmender Ausgangsspannung kleiner, d. h. die Kurve fÄllt flacher ab, steuert jedoch Ähnlichen Endwerten zu. Mit zunehmender Dehnungsgeschwindigkeit wird die Relaxation grö\er. Die Relaxation wird mit zunehmendem Alter kleiner. Der Alterseinflu\ und die schwÄchere Relaxation der Sehnen von Frauen ist durch die unterschiedlichen SehnenquerschnittflÄchen nicht zu erklÄren.
    Notes: Abstract If a tendon is extended to a certain stress, and the elongation kept constant, the strain decreases, at first fast, then slower. This “stress relaxation” was investigated systematically in 177 not embalmed tendons of the long and short peroneus muscle of human cadavers (39 to 93 years of age) with varying initial stress. The values of stress relaxation measured after 5 and 60 sec were analysed statistically. Stress relaxation after 60 sec is nearly proportional to the initial stress, the relative relaxation after 5 sec decreases with increasing initial stress, i.e. the negative slope of the relaxation curve is not that steep but runs towards similar final values. With increasing age relaxation diminishes. The influence of age and the smaller relaxation in tendons of females cannot be explained by varying cross section areas of tendons.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 40 (1995), S. 287-295 
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Capillary zone electrophoresis ; Enantioseparation ; Carnitine ; Derivatization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Carnitine is an essential component in tissues of animals, higher plants and many microorganisms. Whereas the L-carnitine enantiomer plays an important role in the metabolism of long chain fatty acids, D-carnitine has a considerable toxic influence on biochemical processes. The analytical separation of D-and L-carnitine depends upon derivatization with UV-or fluorescently active substances, e.g. FMOC and (+)/(−)-FLEC. The separation of diastereomeric (+)- and (−)-FLEC carnitine esters was performed successfully with capillary zone electrophoresis (CZE) and HPLC, after optimization of the derivatization process and of the composition and pH of the buffer, using UV- and fluorescence detection. With HPLC separation a detection limit of the carnitine esters of 5 μmol/l when using fluorescence detection was achieved. With both separation systems baseline resolution and short analysis times could be obtained. The enantiomeric FMOC derivatives could be separated using the electrophoretic system and acidic buffers with high concentrations of an osmotic flow modifier together with γ-cyclodextrine as chiral selector. The applicability of the optimized separation conditions are demonstrated in the analysis of agar culture medium inoculated withPseudomonas putida and of pharmaceutical formulations. In all samples very low amounts of D- or L-carnitine could be determined in the presence of the other enantiomeric form. Problems caused by the impurity of the carnitine standards or the derivatization agent (+)/(−)-FLEC are discussed.
    Type of Medium: Electronic Resource
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