ISSN:
0170-2041
Keywords:
α-Amino phosphonic acids
;
Nitrones
;
Oxime ethers
;
oxoiminium salts
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The oxoiminium salts 4a, b, and 8 obtained by alkylation with Et3OBF4 of the aldonitrones 3a, b, and 7 react with diphenyl hydrogen phosphite to give the N-alkoxy α-amino phosphonic esters 6 and 9a, b. Similarly, the cyclic imine oxides 10a, b and the cyclic oxime ethers 14a, b afford the α-branched N-alkoxy α-amino phosphonic esters 12a, b and 16a, b, respectively. Hydrogenolysis and ester hydrolysis affords the α-methyl α-amino phosphonic acid hydrochlorides 13a, b and 17a, b.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199119910129
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