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  • Analytical Chemistry and Spectroscopy  (2)
  • General Chemistry  (2)
  • Circadian rhythms  (1)
  • Magnetencephalographie  (1)
  • 1
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Schizophrenie ; Magnetencephalographie ; Akustisch-evozierte Felder ; Geschlechtsunterschiede ; Hemisphärenasymmetrie ; Key words Schizophrenia ; Magnetoencephalography ; Acoustically evoked fields ; Gender differences ; Hemispheric asymmetry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In this magnetoencephalography study the issue of hemispheric lateralisation in patients with schizophrenia was addressed using acoustically evoked neuromagnetic fields. The characteristics of dipoles in the superior temporal gyrus, the primary auditory cortex, were calculated. In contrast to other studies, alterations did not concern the localisation, but rather the orientation of dipoles. Of pathophysiological interest was that the dipoles abnormalities were found left-hemispherically in male (p=0.02) and right-hemispherically in female patients with schizophrenia (p=0.01) when compared to controls. The findings suggest gender-specific alterations of hemispheric lateralisation in schizophrenia.
    Notes: Zusammenfassung In dieser Magnetenzephalographiestudie wurde die Frage der Hemisphärenlateralisation bei Patienten mit einer Schizophrenie mittels akustisch evozierter neuromagnetischer Felder untersucht und die Charakteristika von Dipolen berechnet, die im Bereich des Gyrus temporalis superior, dem primären Hörkortex, entstehen. Im Gegensatz zu Vorbefunden betrafen die Alterationen weniger die Dipollokalisation als vielmehr die Dipolorientierung. Pathophysiologisch aufschlußreich war, daß die Dipolabweichungen im Vergleich zu Kontrollen bei männlichen Schizophrenen linkshemisphärisch (p=0,02), bei weiblichen Schizophrenen rechtshemisphärisch (p=0,01) nachweisbar waren. Dieses Ergebnis spricht für geschlechtsspezifische Unterschiede der Hemisphärenlateralisation bei Schizophrenien.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 238 (1989), S. 203-207 
    ISSN: 1433-8491
    Keywords: Narcolepsy ; Bright white light ; Circadian rhythms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Bright white light (5001x) for 4 h/day was applied to seven narcoleptic patients (age 47–65 years, mean 55 years). The effects of the light on the disturbed sleep-wake cycle in narcoleptics were investigated by the measurement of the following parameters: (1) excessive daytime sleepiness and sustained attention (multiple sleep latency test); (2) rest-activity cycles; (3) self-ratings (mood, anxiety, tiredness); (4) urinary cycles of 6-OH melatonin sulphate and cortisol; (5) sleep EEG. Treatment with bright light showed neither objective nor subjective changes in the clinical symptoms of narcolepsy. While similar “dosage” light applications can phase shift human circadian rhythms and improve depression and hypersomnia in winter depression, it is not an appropriate treatment for narcolepsy.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 75 (1963), S. 825-830 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In der letzten zusammenfassenden Darstellung unserer Untersuchungen auf dem Säureamid-Gebiet [1] hatten wir u. a. über Darstellung und Reaktionen des Trisformaminomethans berichtet. Die weitere Beschäftigung mit dieser Verbindung führte zu einfachen Synthesen vornehmlich von Heterocyclen. Im Rahmen dieser Synthesen wurden für Formylierung und Ringschluß außer Trisformaminomethan noch andere Verbindungen wie Ameisensäureester, Orthoameisensäureester, Formamidin, Dimethylformamidacetal und Formamid eingesetzt. Über einen Teil dieser neuen Untersuchungen soll im folgenden berichtet werden.
    Additional Material: 6 Tab.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 10 (1977), S. 52-55 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The position of the lanthanide atom calculated from the pseudocontact shift equation was studied for 2-adamantanol and 2-methyl-, 2-ethyl-, 2-propyl-, 2-butyl-2-adamantanol. The possible methods of calculation considering rotation of the methyl group were ascertained in the case of 2-methyl- and 2-ethyl-2-adamantanol. It follows from these results that a 2-alkyl group affects the effective position of the lanthanide atom. The conformational analysis of 2-ethyl-2-adamantanol demonstrates a difference among conformations obtained with various shift reagents. A comparison with extended Huckel theory calculations shows that the shift reagent method can be used only for a qualitative determination of the most advantageous conformation of the ethyl group.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 7 (1975), S. 529-531 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A quantitative interpretation of 1H NMR spectra of symmetrically disubstituted adamantane derivatives (2,4-adamantanedione, 2,6-adamantanedione and 2,4-adamantanetdiol) with shift reagents is reported. Assumptions are made of shift additivity and an average coordination of one molecule of the shift reagent to both functional groups. A much better fit between the experimental and the calculated set of limiting-induced shifts was obtained for calculations based on shift additivity.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 2 (1963), S. 655-659 
    ISSN: 0570-0833
    Keywords: s-Triazines ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In the last account of our investigations in the amide field [1], we reported inter alia on the preparation and reactions of trisformamidomethane. Further work with this compound led to simple syntheses particularly of heterocyclic compaunds. Following the pattern of these syntheses, compounds other than trisformamidomethane were employed for formylation and ring-closure; these included formates, orthoformates, formamidine, dimethylformamide diethylacetal, and formamide. Part of this recent research is reported below.
    Additional Material: 6 Tab.
    Type of Medium: Electronic Resource
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