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  • 1
    ISSN: 1573-0794
    Keywords: Comet Hale–Bopp (1995 O1), ; coma morphology ; spin axis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Monitoring of the near-nucleus activity of C/1995 O1 (Hale-Bopp) began in Teide Observatory in August 1995. During 1996 the comet was observed on 72 nights between March 26 and November 13. A permanent fan structure was observed towards the north during the whole period of observation. The position angle of the axis of this fan was measured and its variations with time were used to determine the position of the North Pole of the cometary nucleus.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 63 (1991), S. 54-55 
    ISSN: 1432-0584
    Keywords: Fanconi's anemia ; Androgens ; Squamous cell carcinoma ; Liver neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Acute leukemia, hepatocellular carcinoma, and squamous cell carcinoma have been reported in patients with Fanconi's anemia. We report on a 31-year-old woman who developed squamous cell carcinoma of the esophagus and hepatocellular carcinoma. Jaundice and hepatic tumor developed in 1981, after she had received oxymetholone for 10 years. Liver biopsy revealed peliosis hepatis. Androgenic therapy was stopped and the jaundice resolved. However, the hepatic tumor was observed to be unchanged. The patient died of disseminated squamous cell carcinoma, but no metastatic lesions from hepatocellular carcinoma were detected in the autopsy. The association of Fanconi's anemia and squamous cell carcinoma is reviewed, and the malignant potential of androgen-related hepatic tumors is discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 321 (1982), S. 112-115 
    ISSN: 1432-1912
    Keywords: Diazepam ; Tofizopam ; Rat brain levels ; Benzodiazepine receptors ; Anticonvulsant effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of tofizopam on 3H-flunitrazepam binding was studied in rat hippocampus and cerebellum. Tofizopam (at a concentration of 10−7M) increased 3H-Flu binding through a 30% rise in the B max with no modification of K d in either brain area. Similar results were obtained when the binding was measured in tofizopam (50 mg/kg p.o.) pretreated rats. Even though tofizopam has no anticonvulsive action against pentetrazol-induced convulsions, it significantly potentiated the action of diazepam but with no modification of brain diazepam levels and metabolism. The brain levels of tofizopam are reported and compared to plasma levels after oral administration of 5 and 50 mg/kg to rats.
    Type of Medium: Electronic Resource
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