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  • Angiogenesis  (2)
  • Astrocytic melanization  (1)
  • Atresia  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The angiogenesis of micrencephalic rat brains caused by methylazoxymethanol acetate (1985)
    Springer
    Acta neuropathologica 66 (1985), S. 253-263 
    Details
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angiogenesis of the rat cerebrum was studied under pathologic conditions caused by the administration of the neurotoxin methylazoxymethanol acetate (MAMAc) in the time (E14) of neuroblast migration. The sinovenous junction of the main superficial cerebral veins and the morphological changes of the veins were examined by a quantitative analytic method. The hypoplastic areas of the brains showed extremely malformed venous systems with pathologic changes of the sinovenous junctions depending on the degree of disturbance of the neuroblast migration. These findings suggest the primary role of the neuronal maturation in the angioarchitectonic development and the direct dependency of the vascular differentiation on the neuroblast migration of the drained territory.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688591
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Dandy-Walker syndrome with atresia of the fourth ventricle and multiple rhombencephalic malformations (1982)
    Springer
    Acta neuropathologica 58 (1982), S. 81-86 
    Details
    ISSN: 1432-0533
    Keywords: Dandy-Walker ; Vermis aplasia ; Atresia ; Fourth ventricle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of Dandy-Walker syndrome associated with multiple maldevelopmental lesions of the brain stem and cerebellum is presented. The additional malformations include hypoplasia of both cerebellar hemispheres with multiple foci of cortical dysplasias, rostral dilatation of the fourth ventricle and atresia in its caudal part, hypoplasia of the basis pontis, displacement and dysplasia of several nuclear groups of the medulla oblongata, including subtotal aplasia of the inferior olivar complex, and incomplete decussation of the pyramidal tracts. These lesions implicate a hindrance of neuroblastic proliferation and migration from rhombencephalic cytogenetic zones of the entire alar plate with peristent anterior membranous area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691645
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    The angiogenesis of micrencephalic rat brains caused by methylazoxymethanol acetate (1985)
    Springer
    Acta neuropathologica 68 (1985), S. 59-64 
    Details
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angioarchitecture of the superficial and basal arterial system of the hypoplastic rat brain caused by the administration of the neurotoxin, methylazoxymethanol acetate (MAMAc), at the time of neuroblast migration was studied. Increased variation of the arterial branching of the basal main stem of arteries and local vessel changes were observed. The findings suggest a close relationship between vascular and neuronal development, showing a generalized disturbance and local adaptation of vasculature to the altered neuronal architecture of the corresponding hypoplastic areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688957
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Striato-nigral astrocytic melanization (1979)
    Springer
    Journal of neurology 220 (1979), S. 149-156 
    Details
    ISSN: 1432-1459
    Keywords: Melanin ; Astrocytic melanization ; Striato-nigral degeneration ; Catecholamine metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bericht über 2 nicht verwandte Patientinnen, die eine abnormale Pigmentierung des Striatum und der Substantia nigra zeigten. Beide litten an debilitierenden Gelenkerkrankungen, aber hatten keine Geschichte neurologischer Symptomatik. Das abnormale Pigment fand sich in Astrocyten und hatte die histochemischen Eigenschaften und die Feinstruktur von Melanin. Die Veränderungen weisen auf eine Störung des Katecholaminstoff-wechsels hin, wobei offen bleibt, of dieselbe endogen ist oder auf unbekannten exogenen Faktoren beruht.
    Notes: Summary Abnormal pigmentation was found in the striatum, pallidum and substantia nigra of two unrelated patients. Both had suffered from debilitating joint disease; there was no evidence of a progressive neurologic disorder. The pigment was localized in astrocytes and had the histochemical and electron microscopic features of melanin. The tissue changes suggest an anomaly of catecholamine metabolism either endogenous or induced by a still unknown exogenous factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00705533
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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