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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 177 (1987), S. 115-121 
    ISSN: 1432-0568
    Keywords: Myelin sheath thickness ; g Ratio ; Peripheral nerves ; Autonomic nerves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Computer-assisted measurements of relative myelin sheath thickness (the g ratio) were made in 11 peripheral nerves of the rat. The scatter diagrams showed nerve-specific variations in the distribution of relative myelin sheath thickness. Myelinated fibers of less than 3.5 μm axon diameter had relatively thin myelin sheaths, particularly in the splanchnic, vagus and glossopharyngeal nerves. The oculomoter nerve had two fiber populations clearly set apart in terms of relative myelin sheath thickness. Thickly myelinated fibers were found in facial and hypoglossal nerves. No single functional modality was evident for the thinly myelinated fibers
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 55 (1981), S. 75-76 
    ISSN: 1432-0533
    Keywords: Rosenthal fibers ; Glial fibrillary acid protein ; Astrocytoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixteen cases of pilocytic astrocytomas with excessive Rosenthal fiber (RF) formation were examined by the indirect immunoperoxidase method for the localization of glial fibrillary acid protein (GFAP). RF nerve contained GFAP but they were often enclosed in plump and thickened GFAP-positive astrocytic processes. The border between the negative RF and the surrounding positive rim of cytoplasm was always sharp and without gradual transitions. The antigenic difference between RFs and glial filaments imply that glial filaments undergo a profound change in their chemical composition during their transformation into RFs. The possibility that RFs are not degradation products of glial filaments but consist of some chemically unknown substance produced by metabolically activated astrocytes cannot be excluded.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 178 (1988), S. 537-541 
    ISSN: 1432-0568
    Keywords: Myelin sheath thickness ; g Ratio ; Frog sciatic nerve ; Axon caliber
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Frog sciatic nerves show a continuing addition of new myelinated and nonmyelinated fibers with body growth. Along with increases in fiber number there are also marked changes in axon calibers and in the relative thickness of the myelin sheaths. Our data show that frog nerves, as opposed to mammalian nerves, are composed of fibers of different ages, stages of growth and stages of myelination.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 66 (1985), S. 253-263 
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angiogenesis of the rat cerebrum was studied under pathologic conditions caused by the administration of the neurotoxin methylazoxymethanol acetate (MAMAc) in the time (E14) of neuroblast migration. The sinovenous junction of the main superficial cerebral veins and the morphological changes of the veins were examined by a quantitative analytic method. The hypoplastic areas of the brains showed extremely malformed venous systems with pathologic changes of the sinovenous junctions depending on the degree of disturbance of the neuroblast migration. These findings suggest the primary role of the neuronal maturation in the angioarchitectonic development and the direct dependency of the vascular differentiation on the neuroblast migration of the drained territory.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 68 (1985), S. 59-64 
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angioarchitecture of the superficial and basal arterial system of the hypoplastic rat brain caused by the administration of the neurotoxin, methylazoxymethanol acetate (MAMAc), at the time of neuroblast migration was studied. Increased variation of the arterial branching of the basal main stem of arteries and local vessel changes were observed. The findings suggest a close relationship between vascular and neuronal development, showing a generalized disturbance and local adaptation of vasculature to the altered neuronal architecture of the corresponding hypoplastic areas.
    Type of Medium: Electronic Resource
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