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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 66 (1985), S. 253-263 
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angiogenesis of the rat cerebrum was studied under pathologic conditions caused by the administration of the neurotoxin methylazoxymethanol acetate (MAMAc) in the time (E14) of neuroblast migration. The sinovenous junction of the main superficial cerebral veins and the morphological changes of the veins were examined by a quantitative analytic method. The hypoplastic areas of the brains showed extremely malformed venous systems with pathologic changes of the sinovenous junctions depending on the degree of disturbance of the neuroblast migration. These findings suggest the primary role of the neuronal maturation in the angioarchitectonic development and the direct dependency of the vascular differentiation on the neuroblast migration of the drained territory.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 58 (1982), S. 81-86 
    ISSN: 1432-0533
    Keywords: Dandy-Walker ; Vermis aplasia ; Atresia ; Fourth ventricle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of Dandy-Walker syndrome associated with multiple maldevelopmental lesions of the brain stem and cerebellum is presented. The additional malformations include hypoplasia of both cerebellar hemispheres with multiple foci of cortical dysplasias, rostral dilatation of the fourth ventricle and atresia in its caudal part, hypoplasia of the basis pontis, displacement and dysplasia of several nuclear groups of the medulla oblongata, including subtotal aplasia of the inferior olivar complex, and incomplete decussation of the pyramidal tracts. These lesions implicate a hindrance of neuroblastic proliferation and migration from rhombencephalic cytogenetic zones of the entire alar plate with peristent anterior membranous area.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 68 (1985), S. 59-64 
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angioarchitecture of the superficial and basal arterial system of the hypoplastic rat brain caused by the administration of the neurotoxin, methylazoxymethanol acetate (MAMAc), at the time of neuroblast migration was studied. Increased variation of the arterial branching of the basal main stem of arteries and local vessel changes were observed. The findings suggest a close relationship between vascular and neuronal development, showing a generalized disturbance and local adaptation of vasculature to the altered neuronal architecture of the corresponding hypoplastic areas.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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