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  • Angiogenesis  (2)
  • Macrophage recruitment  (2)
  • g Ratio  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Characteristic variations of relative myelin sheath thickness in 11 nerves of the rat (1987)
    Springer
    Anatomy and embryology 177 (1987), S. 115-121 
    Details
    ISSN: 1432-0568
    Keywords: Myelin sheath thickness ; g Ratio ; Peripheral nerves ; Autonomic nerves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Computer-assisted measurements of relative myelin sheath thickness (the g ratio) were made in 11 peripheral nerves of the rat. The scatter diagrams showed nerve-specific variations in the distribution of relative myelin sheath thickness. Myelinated fibers of less than 3.5 μm axon diameter had relatively thin myelin sheaths, particularly in the splanchnic, vagus and glossopharyngeal nerves. The oculomoter nerve had two fiber populations clearly set apart in terms of relative myelin sheath thickness. Thickly myelinated fibers were found in facial and hypoglossal nerves. No single functional modality was evident for the thinly myelinated fibers
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572535
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The number of frog sciatic axons increases continually during body growth (1988)
    Springer
    Anatomy and embryology 178 (1988), S. 537-541 
    Details
    ISSN: 1432-0568
    Keywords: Myelin sheath thickness ; g Ratio ; Frog sciatic nerve ; Axon caliber
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Frog sciatic nerves show a continuing addition of new myelinated and nonmyelinated fibers with body growth. Along with increases in fiber number there are also marked changes in axon calibers and in the relative thickness of the myelin sheaths. Our data show that frog nerves, as opposed to mammalian nerves, are composed of fibers of different ages, stages of growth and stages of myelination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00305041
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Mechanisms of macrophage recruitment in Wallerian degeneration (1995)
    Springer
    Acta neuropathologica 89 (1995), S. 363-367 
    Details
    ISSN: 1432-0533
    Keywords: Key words C57BL/Ola mice ; Macrophage recruitment ; Myelin removal ; Wallerian degeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Monocytes/macrophages are important effector cells in myelin removal during Wallerian degeneration. Experiments with the mouse mutant C57BL/Ola revealed prolonged axonal survival and reduced phagocytic cell recruitment after nerve transsection. In the present study, we compared the course of Wallerian degeneration in peripheral nerves of C57BL and C57BL/Ola mice in vivo and in vitro. In vivo experiments confirmed earlier investigations describing a delayed d egeneration in the C57BL/Ola mutant compared with C57BL mice which were used as control animals without abnormal degeneration. Quite different results were seen in experiments in vitro: degenerating nerve segments of C57BL/Ola mice revealed pronounced axonal breakdown even in the absence of non-resident phagocytic cells. There was no difference in vitro compared with degenerating nerves from C57BL mice. The differences observed between the in vivo and in vitro situations suggest that axonal breakdown plays an important role in the initiation of macrophage recruitment to degenerating peripheral nerves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00309630
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Mechanisms of macrophage recruitment in Wallerian degeneration (1995)
    Springer
    Acta neuropathologica 89 (1995), S. 363-367 
    Details
    ISSN: 1432-0533
    Keywords: C57BL/Ola mice ; Macrophage recruitment ; Myelin removal ; Wallerian degeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Monocytes/macrophages are important effector cells in myelin removal during Wallerian degeneration. Experiments with the mouse mutant C57BL/Ola revealed prolonged axonal survival and reduced phagocytic cell recruitment after nerve transsection. In the present study, we compared the course of Wallerian degeneration in peripheral nerves of C57BL and C57BL/Ola mice in vivo and in vitro. In vivo experiments confirmed earlier investigations describing a delayed degeneration in the C57BL/Ola mutant compared with C57BL mice which were used as control animals without abnormal degeneration. Quite different results were seen in experiments in vitro: degenerating nerve segments of C57BL/Ola mice revealed pronounced axonal breakdown even in the absence of non-resident phagocytic cells. There was no difference in vitro compared with degenerating nerves from C57BL mice. The differences observed between the in vivo and in vitro situations suggest that axonal breakdown plays an important role in the initiation of macrophage recruitment to degenerating peripheral nerves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00309630
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    The angiogenesis of micrencephalic rat brains caused by methylazoxymethanol acetate (1985)
    Springer
    Acta neuropathologica 66 (1985), S. 253-263 
    Details
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angiogenesis of the rat cerebrum was studied under pathologic conditions caused by the administration of the neurotoxin methylazoxymethanol acetate (MAMAc) in the time (E14) of neuroblast migration. The sinovenous junction of the main superficial cerebral veins and the morphological changes of the veins were examined by a quantitative analytic method. The hypoplastic areas of the brains showed extremely malformed venous systems with pathologic changes of the sinovenous junctions depending on the degree of disturbance of the neuroblast migration. These findings suggest the primary role of the neuronal maturation in the angioarchitectonic development and the direct dependency of the vascular differentiation on the neuroblast migration of the drained territory.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688591
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    The angiogenesis of micrencephalic rat brains caused by methylazoxymethanol acetate (1985)
    Springer
    Acta neuropathologica 68 (1985), S. 59-64 
    Details
    ISSN: 1432-0533
    Keywords: Angiogenesis ; Micrencephaly ; MAMAc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The angioarchitecture of the superficial and basal arterial system of the hypoplastic rat brain caused by the administration of the neurotoxin, methylazoxymethanol acetate (MAMAc), at the time of neuroblast migration was studied. Increased variation of the arterial branching of the basal main stem of arteries and local vessel changes were observed. The findings suggest a close relationship between vascular and neuronal development, showing a generalized disturbance and local adaptation of vasculature to the altered neuronal architecture of the corresponding hypoplastic areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688957
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    Paper (German National Licenses)
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