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  • Polymer and Materials Science  (17)
  • Cell & Developmental Biology  (5)
  • Angiotensin II  (4)
  • Coexistence  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Somatostatin- and enkephalin-like immunoreactivities are frequently colocalized in neurons in the caudal brain stem of rat (1987)
    Springer
    Experimental brain research 67 (1987), S. 420-428 
    Details
    ISSN: 1432-1106
    Keywords: Peptides ; Coexistence ; Nucleus tractussolitarii ; Ventral medulla ; Immunohistochemistry ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The medulla oblongata and pons of colchicine treated rats were analyzed with a doublestaining technique using mouse monoclonal antibodies to somatostatin and rabbit polyclonal antibodies raised against methionine-enkephalin. Numerous cells reacted with both antisera but cells reacting with only one antiserum were also observed. Double-stained cells were most frequently encountered at all levels of the nucleus tractus solitarii, in a well defined group in the caudal medullary reticular formation, along the lateral ventral surface of the medulla oblongata, dorsolateral to the inferior olive and in the nucleus raphe magnus. These findings provide further examples of coexistence of two peptides and indicate the possibility that somatostatin-and enkephalin-like peptides are co-released.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00248562
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  • 2
    Electronic Resource
    Electronic Resource
    Dopaminergic cells in the caudal A13 cell group express somatostatin-like immunoreactivity (1987)
    Springer
    Experimental brain research 67 (1987), S. 441-444 
    Details
    ISSN: 1432-1106
    Keywords: Dopamine ; Somatostatin ; Immunocytochemistry ; Coexistence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The caudal extension of the hypothalamic A13 dopamine cell group (A13c) was studied in the rat brain with immunohistochemical techniques using antibodies raised against the dopamine synthesizing enzymes tyrosine hydroxylase (TH) and aromatic L-amino acid decarboxylase (AADC). Adjacent sections revealed that the TH- and AADC-staining patterns exhibited a clear overlap with that for somatostatin (SOM). Employing a double-labelling method with SOM- and AADC-antisera and subsequent elution and restaining of the same section with TH-antiserum, it was found that all immunoreactivities occurred in the same cell bodies. This study gives the first evidence for the presence of SOM-immunoreactivity in dopamine neurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00248566
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  • 3
    Electronic Resource
    Electronic Resource
    Glomerular ultrastructure of the trout, Salmo gairdneri: Effects of angiotensin II and adaptation to seawater (1987)
    Springer
    Cell & tissue research 249 (1987), S. 437-442 
    Details
    ISSN: 1432-0878
    Keywords: Angiotensin II ; Glomerulus ; Salmo gairdneri ; Seawater-adaptation ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effect of angiotensin infusion on the glomerular ultrastructure of freshwater- and seawater-adapted rainbow trout, Salmo gairdneri, has been examined by scanning and transmission electron microscopy. Adaptation of trout to seawater resulted in epithelial podocyte flattening, primary process broadening and apparent loss of foot processes in almost all glomeruli, features which were uncommon in freshwater-adapted trout. Similar changes were induced by infusion of freshwater-adapted animals with angiotensin, suggesting that the renin-angiotensin system plays a role in the modification of glomerular epithelial ultrastructure. Adaptation of trout to seawater also reduced glomerular diameter, but infusion of freshwater-adapted animals with angiotensin did not mirror this effect. Infusion of angiotensin into seawater-adapted animals increased the overall thickness of glomerular basement membrane by increasing the lamina rara interna and lamina densa. This did not occur when freshwater-adapted fish were either infused with angiotensin or adapted to seawater. These findings suggest that other humoral systems are involved in the control of glomerular diameter and basement membrane thickness as part of an integrated response to increased environmental salinity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00215528
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  • 4
    Electronic Resource
    Electronic Resource
    Glomerular binding of angiotensin II in the rainbow trout,Salmo gairdneri (1990)
    Springer
    Cell & tissue research 259 (1990), S. 479-482 
    Details
    ISSN: 1432-0878
    Keywords: Kidney ; Glomerulus ; Angiotensin II ; Salmo gairdneri (Teleostei)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Isolated glomeruli of the rainbow trout have been exposed in vitro to125I-angiotensin II (0.88 × 10−9 M) and binding sites located by light-microscopic autoradiography. These studies provide evidence of specific binding of angiotensin II by glomeruli. Binding was significantly inhibited by excess (10−5 M) unlabelled angiotensin II, but a high degree of non-specific binding also occurred. The mammalian competitive antagonist, saralasin (3 × 10−7 M) did not influence125I-angiotensin II binding to fish glomeruli. Intense binding of125I-angiotensin II was noted at the vascular pole of some glomeruli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01740774
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  • 5
    Electronic Resource
    Electronic Resource
    Primary sensory neurons of the rat showing calcitonin gene-related peptide immunoreactivity and their relation to substance P-, somatostatin-, galanin-, vasoactive intestinal polypeptide- and cholecystokinin-immunoreactive ganglion cells (1987)
    Springer
    Cell & tissue research 247 (1987), S. 417-431 
    Details
    ISSN: 1432-0878
    Keywords: Dorsal root ganglia ; Neuropeptides ; Coexistence ; Immunohistochemistry ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary By use of the indirect immunofluorescence technique the distribution of calcitonin gene-related peptide (CGRP)-like immunoreactivity (LI) has been analyzed in cervical and lumbar dorsal root ganglia of untreated and colchicine-treated rats. In addition, lumbar ganglia were examined 2 weeks after transection of the sciatic nerve. The occurrence of CGRP-positive cells in relation to ganglion cells containing substance P-, somatostatin-, galanin-, cholecystokinin (CCK)-, and vasoactive intestinal polypeptide (VIP)/peptide histidine isoleucin (PHI)-LI has been evaluated on consecutive sections as well as using elution-restaining and double-staining techniques. CGRP-LI was observed in many ganglion cells of all sizes ranging in diameter from 15 μm to 65 μm. Thus, this peptide occurs also in the large primary sensory neurons. In contrast to the sensory peptides described to date, CGRP-positive cells constituted up to 50% of all and 70% of the medium-sized neurons, thus being the most frequently occurring peptide in sensory neurons so far encountered. Subpulations of CGRP-positive neurons were shown to contain substance P-, somatostatin-, or galanin-LI and some CGRP-positive neurons contained both substance P- and galanin-LI. In fact, most substance P-, somatostatin- and galanin-positive cell bodies were CGRP-immunoreactive. The coexistence analysis further revealed that galanin and substance P often coexisted and that some cells contained both substance P- and somatostatin-LI, whereas no coexistence between galanin and somatostatin has as yet been seen. VIP/PHI-LI was only shown in a few cells in untreated or colchicine-treated rats. However, after transcetion of the sciatic nerve numerous VIP/PHI-positive cells were observed, some of which also contained CGRP-LI. The present results indicate that a CGRP-like peptide is present in a wide range of primary sensory neurons probably not related to specific sensory modalities. Often this peptide coexists with other biologically active peptides. Taken together these findings suggest that CGRP may have a generalized function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00218323
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  • 6
    Electronic Resource
    Electronic Resource
    Direct effects of angiotensin II on glomerular ultrastructure in the rainbow trout, Salmo gairdneri (1990)
    Springer
    Cell & tissue research 260 (1990), S. 315-319 
    Details
    ISSN: 1432-0878
    Keywords: Glomerulus ; Angiotensin II ; Glomerular ultrastructure ; Seawater adaptation ; Salmo gairdneri (Teleostei)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Slices from the kidneys of the rainbow trout which were exposed to 10-6 or 10-5 M angiotensin II (AII) and isolated glomeruli exposed to 10-7 or 10-5 M AII showed ultrastructural changes compared to control tissues incubated without AII. The studies indicate that angiotensin II has a direct action on glomerular ultrastructure, flattening the epithelial podocytes and broadening the primary processes with fusion of pedicels in extreme cases. These changes suggest a probable effect of AII on water permeability of the trout glomerulus, an intrarenal action which is believed to form an essential part of the antidiuretic adaptation to increased environmental salinities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00318634
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  • 7
    Electronic Resource
    Electronic Resource
    Observations on preadipocytes and their distribution patterns in rat adipose tissue (1981)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 168 (1981), S. 281-288 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Microscopic examination of adipocytes isolated from adult rat epididymal adipose tissue revealed numerous small cells (〈 10 μm) morphologically similar to larger adipocytes. These small adipocytes appear identical to a new classification of adipose cells termed preadipocytes. Electron micrographs of these preadipocytes revealed examples of cells 〈 10 μm in diameter in various stages of maturation and lipid accumulation. The percent distribution pattern of these small adipocytes was not significantly altered by exercise although exercise shifted the distribution patterns of the larger cells (〉 30 μm) toward a smaller mean cell size. The quantitative significance of preadipocytes is not established but these preliminary observations indicate that adipocytes 〈 10 μm in diameter may account for a numerically greater proportion of the total adipocytes observed in collagenase isolated preparations than heretofore recognized, although their contribution to total adipose mass is probably negligible.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051680304
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of gamma radiation on two aromatic polysulfones (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 19 (1975), S. 405-417 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Two aromatic polysulfones, poly(oxy-1,4-phenylenesulfonyl-1,4-phenyleneoxy-1,4-phenyleneisopropylidene-1,4-phenylene) (I) and poly (oxy-1,4-phenylenesulfonyl-1,4-phenylene) (II), undergo crosslinking and chain scission at 30°C during γ-irradiation, the former being predominant in vacuum and the latter in air. Both processes occurred more readily in I, which contains isopropylidene linkages. Gel measurements gave G(crosslink) = 0.051, G(scission) = 0.012 for this polymer at 30°C in vacuum. Increased irradiation temperatures resulted in higher crosslinking and gas yields, especially above the glass transition temperature. The tensile strength, flexural strength, and modulus of I were unaffected by γ-irradiation up to about 50 Mrad in air, but the strength decreased markedly at higher doses. The elongation at break decreased progressively with dose. For both polymers, G(gas) = 0.04 at 30°C with the main products being SO2, H2, CO2, CH4, and H2O.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1975.070190208
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  • 9
    Electronic Resource
    Electronic Resource
    Angiotensin II binding to tissues of the rainbow trout, Oncorhynchus mykiss, studied by autoradiography (1992)
    Springer
    Journal of comparative physiology 162 (1992), S. 197-202 
    Details
    ISSN: 1432-136X
    Keywords: Angiotensin II ; Autoradiography ; Seawater-adaptation ; trout, Oncorhynchus mykiss (= Salmogairdneri)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Tissue slices from seawater-adapted and freshwater-adapted rainbow trout, Oncorhynchus mykiss, were exposed to 125I-angiotensin II (1.01·10-9 M) and binding sites located by light-microscopic autoradiography. Binding/uptake was significantly inhibited by excess (10-5 M) unlabelled angiotensin II, suggesting specific binding/uptake of angiotensin II to the ventral and dorsal aorta (smooth muscle), urinary bladder (smooth muscle and epithelial lining), glomeruli and proximal tubules, the gill (lamellae and central filament), skin (epithelium), intestine and oesophagus (mucosal epithelium), liver, heart (ventricular myocytes), adrenocortical tissue and brain (cerebellum and medulla oblongata). The specific binding/uptake of angiotensin II to tissues of freshwater- and seawater-adapted animals were generally similar. However, binding/uptake by the proximal tubules was significantly higher in freshwater-adapted trout than seawater-adapted trout. Specific binding/uptake of angiotensin II by the smooth muscle of the bladder was significantly higher in trout adapted to seawater than trout adapted to freshwater.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00357523
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  • 10
    Electronic Resource
    Electronic Resource
    The effect of hydrogen chloride on the corrosion of an FeCrAlY alloy in simulated coal gasifier atmospheres (1989)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 40 (1989), S. 175-181 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Einfluß von Chlorwasserstoff auf die Korrosion einer FeCrAlY-Legierung in einer simulierten KohlevergasungsatmosphäreEie Chrom-Aluminium-Yttrium-Stahl wurde einer simulierten Kohlevergasungsatmosphäre ausgesetzt die 1000 ppm bzw. 2200 ppm Chlorwasserstoff enthielt und deren Temperatur 450 °C betrug. Durch Erhöhen des Chlorwasserstoffgehalts werden die Reaktionsgeschwindigkeit erhöht und die Mikrostruktur sowie die Zusammensetzung des Korrosionsprodukts beträchtlich verändert. Für diese Ergebnisse werden versuchsweise Mechanismen postuliert, nach denen Metallchloride über die Gasphase transportiert werden.
    Notes: An iron chromium aluminium yttrium steel was exposed to a simulated coal gasifier atmosphere containing 1000 ppm and 2200 ppm hydrogen chloride at 450 °C. Increasing hydrogen chloride content was found to accelerate reaction rates, and significantly alter the microstructure and composition of the corrosion product. Tentative explanations for these results, involving vapour phase transport of metal chlorides are proposed.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19890400312
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