ISSN:
1432-069X
Keywords:
Neisseria gonorrhoeae
;
Auxotyping
;
Antibiotic susceptibility
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In Munich 169 isolates of Neisseria gonorrhoeae were investigated with respect to nutritional profiles (auxotypes) and antibiotic susceptibility. Of the 165 penicillin-susceptible strains 97 proved to be prototrophic (auxotype 1), 42 proline-dependent (auxotype 2). Only 3 arginine-, hypoxanthine- and uracil-dependent strains (auxotype 14) were found. A total of 10 different auxotypes were identified among the non-penicillinase-producing strains and one among the penicillinase producers. The minimal inhibitory concentrations of penicillin G ranged from 0.01 to 1 μg/ml, those of cefuroxime from 0.001 to 4 mg/ml; tetracycline and kanamycin had a narrow spectrum of effective concentrations, from 0.25 to 8 μg/ml and from 4 to 64 μg/ml respectively. The type 14 strains showed the well-known high susceptibility to penicillin G.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00417339
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