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  • 1
    Electronic Resource
    Electronic Resource
    Autoimmune hemolytic anemia in patients with de novo acute myelocytic leukemia (1996)
    Springer
    Annals of hematology 72 (1996), S. 45-47 
    Details
    ISSN: 1432-0584
    Keywords: Autoimmune hemolytic anemia ; Acute myelocytic leukemia ; Antiglobulin test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Autoantibody against erythrocytes has occasionally been observed in patients with de novo acute myelocytic leukemia (AML). However, it is not clear whether this autoantibody in AML patients induces frank hemolysis (autoimmune hemolytic anemia, AIHA), as seen in lymphoid neoplasms. We present two de novo AML patients who showed hemolysis due to antiglobulin test-positive and test-negative AIHA, respectively. AIHA should be considered as one cause of anemia in de novo AML patients, and blood transfusions should be given carefully in such cases to avoid harmful hemolysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00663016
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Kinetics of megakaryocyte progenitor cells in idiopathic thrombocytopenic purpura (1990)
    Springer
    Annals of hematology 61 (1990), S. 303-306 
    Details
    ISSN: 1432-0584
    Keywords: ITP ; CFU-Meg ; DNA synthetic phase ; Megakaryocyte ; Platelet
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The number and proliferative state of megakaryocyte progenitor cells (CFU-Meg) were compared between 13 patients with idiopathic thrombocytopenic purpura (ITP) and hematologically normal controls. The mean frequency of CFU-Meg assayed by the plasma clot method was 27.8 ± 12.2 (± SD)/2×105 bone marrow light-density cells for the ITP patients, which did not differ significantly from the control value of 31.9 ± 16.1. The percentage of CFU-Meg in DNA synthesis estimated by the3H-thymidine suicide technique was 41.3% ± 9.2% in ITP, which was significantly greater than the control value of 27.1% ± 7.4% (P 〈 0.01). The megakaryocyte counts for histological sections prepared from bone marrow aspirates from the ITP patients and controls were 34.5 ± 8.5/mm2 and 11.2 ± 5.8/mm2, respectively, with the difference being highly significant (P 〈 0.001). These results suggest that increased cycling activity in a quantitatively unchanged CFU-Meg pool may lead to increased megakaryocytes in the bone marrow of ITP patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01732882
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Autoimmune hemolytic anemia in patients with de novo acute myelocytic leukemia (1996)
    Springer
    Annals of hematology 72 (1996), S. 45-47 
    Details
    ISSN: 1432-0584
    Keywords: Key words Autoimmune hemolytic anemia ; Acute myelocytic leukemia ; Antiglobulin test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Autoantibody against erythrocytes has occasionally been observed in patients with de novo acute myelocytic leukemia (AML). However, it is not clear whether this autoantibody in AML patients induces frank hemolysis (autoimmune hemolytic anemia, AIHA), as seen in lymphoid neoplasms. We present two de novo AML patients who showed hemolysis due to antiglobulin test-positive and test-negative AIHA, respectively. AIHA should be considered as one cause of anemia in de novo AML patients, and blood transfusions should be given carefully in such cases to avoid harmful hemolysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00663016
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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