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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 51 (2000), S. 612-614 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Keratoakanthom ; Methotrexat ; Injektion ; Keywords Keratoacanthoma ; Methotrexate ; Intralesional injection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract A 53 year old female patient developed a keratoacanthoma, present on the left side of her nose for two months. After repeated unsuccessful trials with cryotherapy, she was treated with intralesional injection of methotrexate performed twice with a weekly internal. This led to complete resolution within 5 weeks. Although controlled studies on the effect of methotrexate in keratoacanthoma are not available, the rapid regression and the good cosmetic result suggest that this therapy may play a beneficial role in treating these lesions especially in problem locations.
    Notes: Zusammenfassung Eine 53 Jahre alte Patientin entwickelte über 2 Monate ein Keratoakanthom am linken Nasenflügel. Nach wiederholten erfolglosen kryotherapeutischen Behandlungsversuchen erfolgten zweimal im Abstand von 7 Tagen intraläsionale Methothrexat-Injektionen, wonach es innerhalb von 5 Wochen zu einer vollständigen Abheilung kam. Obwohl kontrollierte Studien über die Therapie von Keratoakanthomen mit Methotrexat bislang fehlen, legt die schnelle Tumorregression und das gute kosmetische Ergebnis diese Art der Therapie bei operationstechnisch schwierig lokalisierten Tumoren nahe.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-7284
    Keywords: Neisseria gonorrhoeae ; Munich isolates ; Plasmid content ; Serotyping ; Antimicrobial susceptibility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eighty-four strains of Neisseria gonorrhoeae isolated in Munich between January 1987 and June 1988 were characterized in terms of their plasmid content, protein I serovar and susceptibility or resistance to four antimicrobial agents. Eighty two percent of the strains belonged to serogroup 1B, the three most prevalent serovars being 1B-1, 1B-2 and 1B-6. Among the serogroup 1A strains, 1A-2 was the commonest serovar. Fourteen strains (16.7%) lacked the 2.6 Md cryptic plasmid, although two of these strains contained the conjugative gonococcal plasmid. Although some degree of resistance to penicillin and tetracycline was noted, all the strains were sensitive to spectinomycin and cefotiam.
    Type of Medium: Electronic Resource
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