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  • 1
    Electronic Resource
    Electronic Resource
    An American in Paris and the origins of the stereomicroscope (1994)
    Springer
    Development genes and evolution 203 (1994), S. 235-242 
    Details
    ISSN: 1432-041X
    Keywords: Horatio S. Greenough ; Stereomicroscope ; Dissecting microscope ; Binocular ; Carl Zeiss
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A century ago, Horatio S. Greenough, an American living in Paris, persuaded the firm of Carl Zeiss to construct the first low-power stereomicroscope. Fitted by Zeiss with Porro prisms for image erection, this instrument became the ancestor of all stereoscopic dissection microscopes (“binoculars”) now in use. On the basis of original documents and earlier publications, the present Centennial Essay traces both the history of the Greenough stereomicroscope and the scantily documented life of its inventor, including his probable descent from a family of famous New England sculptors. The aim is to provide some historical background for a truly timeless instrument that was fundamental to developmental biology, beginning almost from the days of its proclamation by Wilhelm Roux.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00360518
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    In situ localization of the transcripts of a homeobox gene in the honeybee Apis mellifera L. (Hymenoptera) (1988)
    Springer
    Development genes and evolution 197 (1988), S. 269-274 
    Details
    ISSN: 1432-041X
    Keywords: Apis mellifera ; Homeobox genes ; Dfd ; In situ hybridization ; Blastoderm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We have isolated and characterized a homeoboxcontaining gene from the honeybee Apis mellifera. Its homeobox region shows a high degree of sequence similarity to the homeobox of the Drosophila gene Deformed (Dfd). At the DNA level 82% of the basepairs are the same, whereas the putative amino acid sequences are identical between the bee and the fruitfly genes. Similarity is also present 5′ and 3′ to the homeobox. Using this isolate as a probe we have performed in situ hybridization on sections from blastoderm-stage embryos of the honeybee Apis mellifera. In early blastoderm stages we found a rather irregular pattern of labelled nuclei. In middle stages we found silver grains over each nucleus and also over the cytoplasm in a belt of blastoderm cells in the prospective gnathal region. These results indicate that the Deformed genes from honeybee and fruitfly are homologous both with respect to their DNA sequence and their spatial and temporal pattern of expression during embryogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00380020
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    Paper (German National Licenses)
    Fulltext
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