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  • 1
    Electronic Resource
    Electronic Resource
    Response-oriented therapy with CHOP and VIM-Bleo in high-grade malignant non-Hodgkin's lymphomas (1988)
    Springer
    Annals of hematology 56 (1988), S. 269-271 
    Details
    ISSN: 1432-0584
    Keywords: Non-Hodgkin's lymphomas ; Chemotherapy ; Consolidation therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty four patients with high grade malignant NHL (stage II 8, stage III 4, stage IV 12 patients respectively) were treated with a response-oriented regimen: Treatment was initiated according to the CHOP-protocol. Patients achieving at least a partial remission after 2 and a complete remission (CR) after 4 cycles were continued on CHOP to a total of 9 cycles. Patients not meeting these criteria were switched to a combination of Etoposide, Ifosfamide, Methotrexate, and Bleomycin (VIM-Bleo). With CHOP treatment, 16 patients (67%) achieved a CR. Of the remaining 8, 7 were treated with VIM-Bleo; 5 of these entered CR for a overall CR rate of 21/24 (88%). With a median follow up of 28 months 7 patients relapsed: 6 relapses occurred in patients with a rapid initial response and treated only with CHOP. We conclude, that there is a significant risk of relapse even in patients readily responding to CHOP and that consolidation therapy with a non cross-resistant regimen may improve results in these patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320288
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Sterilitätsbehandlung mit donogener Insemination (2000)
    Springer
    Reproduktionsmedizin 16 (2000), S. 249-252 
    Details
    ISSN: 1434-808X
    Keywords: Schlüsselwörter ; Artifizielle donogene Insemination • Rechtsfragen ; Keywords ; Artificial insemination from the donor • Legal aspects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Therapeutical inseminations from the donor take place in Germany for more than tens of years. The 73th German Phycians × Meeting has given consent in 1970. Today more than 60,000 to 70,000 children live in Germany born after fecundation by donor sperm. Selection of spermdonors takes place in aggreement to international criteria. The priciples of treatment of donogen insemination are in hand as recommendation. But some legal problems demand lawfull regulation for instance anonymity of the donor, law of family and successions, safe-keeping of documents, fees for the donor.
    Notes: Zusammenfassung Therapeutische donogene Inseminationen werden seit mehr als 3 Jahrzehnten in Deutschland durchgeführt. Der 73. Deutsche Ärztetag hatte 1970 seine Zustimmung gegeben. Heute leben in Deutschland mehr als 60.000–70.000 Kinder, die ihr Leben der Befruchtung mit Spendersperma verdanken. Die Auswahl der Spermaspender erfolgt nach international üblichen Kriterien. Es liegen Behandlungsgrundsätze für die donogene Insemination als Empfehlungen vor. Aber einige rechtliche Probleme wie Anonymität des Spenders, Familien- und Erbrecht, Verwahrfrist der Akten, Spenderhonorar bedürfen noch einer gesetzlichen Regelung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004440000194
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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