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  • Astrocytic plaques  (1)
  • Asymptomatic  (1)
  • Conduction velocities  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International urogynecology journal 3 (1992), S. 64-70 
    ISSN: 1433-3023
    Keywords: Asymptomatic ; Microhematuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Asymptomatic microhematuria is not a rare phenomenon among apparently healthy individuals, and the incidence of such hematuria increases significantly with age. Some investigators report that the cause of hematuria is renal glomerular disease in more than 50% of patients, and urological malignancies in 1.0%–13%. On initial examination, urine sediments must be searched for evidence of renal glomerular disease, such as RBC casts and dysmorphic RBCs. If the patients were diagnosed to have glomerular disease, follow-up studies, without any extended examination or therapy are recommended, because their prognosis is usually favorable. The next step is to perform thorough urological examinations, including urine cytology, cystoscopy, abdominal ultrasound, and intravenous pyelography, to detect serious underlying disease. Even if no significant findings were observed after the extensive urological examinations, careful follow-up studies should be performed at 6–12-month intervals for 3 years, using the same methods.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Key words Corticobasal degeneration ; Progressive ; supranuclear palsy ; Astrocytic plaques ; Tufts of ; abnormal fibers ; Gallyas-Braak silver staining
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) are characterized by their unique clinical features and neuronal pathology. Although astrocytic plaques and tufts of abnormal fibers have been suggested to be specific histopathologic markers, recent studies have revealed significant clinicopathologic overlap between CBD and PSP. Based on the distinctive camera lucida profile of astrocytic inclusions on Gallyas-Braak silver staining, we found that astrocytic plaques and tufts of abnormal fibers did not coexist in the same patient among 30 cases of clinically diagnosed CBD, PSP and atypical Parkinson’s disease. Using Tau immunohistochemistry it was difficult to verify the absence of tufts of abnormal fibers. A morphometric analysis revealed that the two groups classified by the presence or absence of astrocytic plaques and tufts of abnormal fibers exhibited significant differences in the density of ballooned neurons and neurofibrillary tangles and degeneration of the subcortical nuclei. Assessment using the NINDS neuropathologic criteria revealed that the cases with astrocytic plaques and tufts of abnormal fibers closely correspond to CBD and typical PSP, respectively. In addition, the cases lacking either of these two astrocytic inclusions had atypical PSP according to the NINDS criteria, and were associated with novel tau-positive astrocytes (spiny astrocytes). We thus conclude that astrocytic plaques and tufts of abnormal fibers are highly characteristic structures for CBD and typical PSP, respectively. We emphasize the importance of strict differentiation between different astrocytic inclusions not only for diagnosis, but also for further studies for elucidation of their role in the disease mechanisms of CBD and PSP.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 41 (1980), S. 75-78 
    ISSN: 1432-1106
    Keywords: Mesencephalic reticulospinal neurons ; Conduction velocities ; Vestibular system, semicir cularcanal inputs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurons that project to the spinal cord were located in the mesencephalic reticular formation outside the interstitial nucleus of Cajal in cerebellectomized cats under chloralose anesthesia. Of these neurons 40% responded only at C1 (reticulospinal N cells) and the remaining 60% responded at C4 also (reticulospinal D cells). Conduction velocities of N cells were significantly slower than those of D cells. N cells and D cells responded similarly to stimulation of the whole vestibular nerves and vestibular nuclei. However, they differ in semicircular canal inputs; N cells were more responsive to canal stimulation. Comparison of properties between mesencephalic reticulospinal and interstitiospinal neurons (Fukushima et al. 1980) showed that many reticulospinal and interstitiospinal neurons have similar properties, suggesting that functionally similar neurons may be found distributed over more than one anatomically defined cell group.
    Type of Medium: Electronic Resource
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