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  • 1
    Electronic Resource
    Electronic Resource
    Application of ^1^3C NMR spectroscopy to paratope mapping for larger antigen-Fab complexes
    Amsterdam : Elsevier
    FEBS Letters 346 (1994), S. 246-250 
    Details
    ISSN: 0014-5793
    Keywords: Antigen-antibody interaction ; Antigen-binding site ; C"H1, the first domain of the constant region of the heavy chain ; C"L, constant region of the light chain ; CDR, complementarity-determining region ; DNS-Lys,N-dansyl-l-lysine ; Ex-A,Pseudomonas aeruginosa exotoxin A ; Exotoxin A (Pseudomonas aeruginosa) ; Fab ; Fab, antigen binding fragment composed ofV"H, V"L C"H1, and C"L ; Fv, antigen binding fragment composed of V"H and V"L ; IgG, immunoglobulin G ; Immunoglobulin G ; Mouse ; NMR, nuclear magnetic resonance ; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis ; V"H, variable region of the heavy chain ; V"L, variable region of the light chain. ; [X,Z]Fab, Fab that is labeled with [1-^1^3C]X and [α-^1^5N]Z ; [X]Fab, Fab labeled with [1-^1^3C]X ; ^1^3C NMR
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0014-5793(94)00486-2
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Microscopic hematuria (1992)
    Springer
    International urogynecology journal 3 (1992), S. 64-70 
    Details
    ISSN: 1433-3023
    Keywords: Asymptomatic ; Microhematuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Asymptomatic microhematuria is not a rare phenomenon among apparently healthy individuals, and the incidence of such hematuria increases significantly with age. Some investigators report that the cause of hematuria is renal glomerular disease in more than 50% of patients, and urological malignancies in 1.0%–13%. On initial examination, urine sediments must be searched for evidence of renal glomerular disease, such as RBC casts and dysmorphic RBCs. If the patients were diagnosed to have glomerular disease, follow-up studies, without any extended examination or therapy are recommended, because their prognosis is usually favorable. The next step is to perform thorough urological examinations, including urine cytology, cystoscopy, abdominal ultrasound, and intravenous pyelography, to detect serious underlying disease. Even if no significant findings were observed after the extensive urological examinations, careful follow-up studies should be performed at 6–12-month intervals for 3 years, using the same methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00372658
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Simultaneous occurrence of prostate cancer and IgE myeloma, a rare hematolymphoid malignancy (2000)
    Springer
    International journal of clinical oncology 5 (2000), S. 334-336 
    Details
    ISSN: 1437-7772
    Keywords: Key words Prostate cancer ; IgE myeloma ; Asymptomatic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An unusual case of the simultaneous occurrence of prostate cancer and IgE myeloma is reported. A 74-year-old man with urinary disturbance and elevated serum prostate-specific antigen level, of 7.4 ng/ml, showed Bence-Jones protein in the urine. Immunoelectrophoresis of the serum showed elevation of IgE kappa monoclonal protein. Radical prostatectomy was performed as a curative therapy for T1c, Gleason 3-2 prostate cancer. The patient has remained free of progression of both the myeloma and the prostate cancer for 26 months after the initial diagnosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00012059
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    Paper (German National Licenses)
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