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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 61 (1983), S. 1171-1179 
    ISSN: 1432-1440
    Keywords: Lipoproteins ; Apoproteins ; Lipoprotein receptors ; Atherosclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Plasma lipoproteins are macromolecular complexes which serve as vehicles for the transport of lipids in the blood in a soluble form. The protein components of lipoproteins are referred to as apoproteins. They apparently direct each lipoprotein to its site of metabolism. It is now evident that lipoprotein receptors on the surface of cells in the liver, extrahepatic tissues and perhaps in the RES mediate the uptake of lipoproteins by these tissues. Understanding the mechanisms of the uptake of atherogenic lipoproteins by the cells will lead to further insights of the etiology of atherosclerosis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 339 (1975), S. 153-160 
    ISSN: 1435-2451
    Keywords: Atherosclerosis ; Risk factors ; Arteriosklerose ; Risikofaktoren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Epidemiologische Untersuchungen haben ergeben, daß eine hohe Cholesterinkonzentration im Plasma mit einem erhöhten Infarktrisiko einhergeht. Neben erhöhten Cholesterinwerten spielen auch Diabetes, Zigarettenrauchen, Hypertonie, Übergewicht und Stress eine Rolle bei der Entstehung der Arteriosklerose. An der Med. Univ-Klinik in Heidelberg konnte gezeigt werden, daß nur 59 % von 753 Männern und 53 % von 348 Frauen die ersten 4 Wochen nach dem Herzinfarkt überlebten und daß Zigarettenrauchen frühzeitig zum Herzinfarkt führt. Nichtraucher hatten ihren ersten Herzinfarkt mit 63 Jahren, Zigarettenraucher dagegen schon mit 53. Diese Ergebnisse zeigen die Bedeutung einer frühzeitigen Erkennung dieser Risikofaktoren.
    Notes: Summary Prospective epidemiologic studies have uniformly demonstrated that a high plasma cholesterol level is indicative of an increased risk of myocardial infarction. Beside elevated serum cholesterol, diabetes, smoking, hypertension, obesity, and stress have been correlated with an elevated incidence of atherosclerosis. At the Medical Department in Heidelberg it was demonstrated that four weeks after myocardial infarction (MI) only 59 percent of 753 men and 53 percent of 348 women were still alive, and that smoking cigarettes leads to early MI. Nonsmokers had their first MI at 63 years, cigarette smokers at the age of 53. These results stress the importance of early detection of the above-mentioned risk factors.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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